Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.42 |
| ▸ | CTSS | P25774 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PTPRC | P08575 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4971083 | 1.00 | CTSK (0.42) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL1162877 | 1.00 | CTSK (0.42) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL18248134 | 0.88 | CTSK (0.46) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL1162846 | 0.86 | TGFBR1 (0.41) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL12805714 | 0.86 | TGFBR1 (0.41) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL8751934 | 0.84 | CYP2D6 (0.36) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL21877891 | 0.84 | GRN (0.38) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL21877890 | 0.84 | GRN (0.38) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL2586168 | 0.84 | MEN1 (0.36) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL1162906 | 0.84 | MEN1 (0.36) | CTSKCTSSMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106188098-B | A kind of hydridization cancer therapy drug and preparation method and application | 广东工业大学 | 2017-11-03 | — | — | CN | claimed |
| CN-106188224-A | A kind of multiple target-point anti-cancer medicine and preparation method and application | 广东工业大学 | 2016-12-07 | — | — | CN | claimed |
| CN-106188098-A | A kind of hydridization cancer therapy drug and preparation method and application | 广东工业大学 | 2016-12-07 | — | — | CN | claimed |
| CN-105566447-A | Peptoid antagonist of anti-apoptosis protein and synthesis method and application of peptoid antagonist | UNIV GUANGDONG TECHNOLOGY | 2016-05-11 | — | — | CN | claimed |
| CN-106188224-B | A kind of multiple target-point anti-cancer drug and the preparation method and application thereof | GUANGDONG UNIVERSITY OF TECHNOLOGY (CN) | 2019-10-29 | — | — | CN | disclosed |
| CN-105566447-B | The class peptide antagonists and its synthetic method of a kind of apoptosis inhibitory protein and application | 广东工业大学 | 2019-09-20 | — | — | CN | disclosed |
| CN-106188098-B | A kind of hydridization cancer therapy drug and preparation method and application | 广东工业大学 | 2017-11-03 | — | — | CN | disclosed |
| CN-106188224-A | A kind of multiple target-point anti-cancer medicine and preparation method and application | 广东工业大学 | 2016-12-07 | — | — | CN | disclosed |
| CN-106188098-A | A kind of hydridization cancer therapy drug and preparation method and application | 广东工业大学 | 2016-12-07 | — | — | CN | disclosed |
| CN-105566447-A | Peptoid antagonist of anti-apoptosis protein and synthesis method and application of peptoid antagonist | UNIV GUANGDONG TECHNOLOGY | 2016-05-11 | — | — | CN | disclosed |
| US-8450301-B2 | Piperazine compounds with a herbicidal action | BASF SE (DE) | 2013-05-28 | — | — | US | disclosed |
| US-20090156553-A1 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2009-06-18 | — | — | US | disclosed |
| EP-1896086-A1 | HYDRAZIDE CONJUGATES AS IMAGING AGENTS | Bristol-Myers Squibb Pharma Company (US) | 2008-03-12 | — | — | EP | disclosed |
| WO-2007005491-A1 | HYDRAZIDE CONJUGATES AS IMAGING AGENTS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2007-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156553-A1 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | DDT, CAT, CIP2A | CTSK 1884/4885CTSS 2211/4885MEN1 4417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.