SCHEMBL28069578

SCHEMBL28069578

Nc1ccc2c(c1)C(=O)c1cccc(Br)c1C2=O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.65
MAPK1 P28482 6/20 0.65
SMN1; SMN2 Q16637 4/20 0.65
NPC1 O15118 3/20 0.65
RAB9A P51151 3/20 0.65
CYP3A4 P08684 3/20 0.65
TSHR P16473 2/20 0.65
TDP1 Q9NUW8 2/20 0.65
TP53 P04637 1/20 0.65
MEN1 O00255 5/20 0.58
KMT2A Q03164 5/20 0.58
PTPRC P08575 4/20 0.58
POLB P06746 4/20 0.58
LMNA P02545 3/20 0.58
ALOX12 P18054 3/20 0.58
HTT P42858 2/20 0.58
NPSR1 Q6W5P4 2/20 0.58
HPGD P15428 2/20 0.58
APAF1 O14727 1/20 0.58
TDP2 O95551 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4444783 0.83 ADORA2A (0.72) ALDH1A1MAPK1SMN1; SMN2NPC1RAB9A
SCHEMBL6905719 0.83 PTPRC (0.61) ALDH1A1MAPK1SMN1; SMN2NPC1RAB9A
SCHEMBL6907201 0.83 PTPRC (0.61) ALDH1A1MAPK1SMN1; SMN2NPC1RAB9A
SCHEMBL8773084 0.83 ADORA2A (0.72) ALDH1A1MAPK1SMN1; SMN2NPC1RAB9A
SCHEMBL29361856 0.83 ADORA2A (0.72) ALDH1A1MAPK1SMN1; SMN2NPC1RAB9A
SCHEMBL30377911 0.83 ADORA2A (0.72) ALDH1A1MAPK1SMN1; SMN2NPC1RAB9A
SCHEMBL472644 0.82 ADORA2A (0.57) ALDH1A1MAPK1SMN1; SMN2NPC1RAB9A
Methylamine SCHEMBL9597386 0.80 ADORA2A (0.57) ALDH1A1MAPK1SMN1; SMN2NPC1RAB9A
SCHEMBL28164455 0.80 ALDH1A1 (0.65) ALDH1A1MAPK1SMN1; SMN2NPC1RAB9A
SCHEMBL21635983 0.80 ALDH1A1 (0.65) ALDH1A1MAPK1SMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105585875-A Dication active dye for salt-free dyeing of cotton fabrics and preparation method thereof NANJING UNIVERSITY OF TECHNOLOGY 2016-05-18 CN disclosed