Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27536598 | 0.86 | MAPT (0.58) | KDM4EALDH1A1TSHRNFKB1L3MBTL1 | |
| SCHEMBL28775127 | 0.83 | NFKB1 (0.73) | KDM4EALDH1A1TSHRNFKB1L3MBTL1 | |
| SCHEMBL10066438 | 0.82 | L3MBTL1 (0.49) | KDM4EALDH1A1TSHRNFKB1L3MBTL1 | |
| SCHEMBL14358094 | 0.81 | P4HTM (0.69) | KDM4EALDH1A1TSHRNFKB1L3MBTL1 | |
| SCHEMBL6138523 | 0.79 | MAPT (0.46) | KDM4EALDH1A1TSHRNFKB1L3MBTL1 | |
| SCHEMBL28252056 | 0.79 | P4HTM (0.49) | KDM4EALDH1A1TSHRNFKB1L3MBTL1 | |
| SCHEMBL2642680 | 0.79 | L3MBTL1 (0.46) | KDM4EALDH1A1TSHRNFKB1L3MBTL1 | |
| SCHEMBL28807057 | 0.79 | MAPK1 (0.56) | KDM4EALDH1A1TSHRNFKB1L3MBTL1 | |
| SCHEMBL10084638 | 0.76 | L3MBTL1 (0.46) | KDM4EALDH1A1TSHRNFKB1L3MBTL1 | |
| SCHEMBL14280836 | 0.75 | KDM4E (0.60) | KDM4EALDH1A1TSHRNFKB1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105566324-A | Hydroxyl purine compound and application thereof | GOOD DOCTOR PHARMACEUTICAL GROUP CO LTD | 2016-05-11 | — | — | CN | disclosed |