Niacin

Niacin

SCHEMBL28069837

O=C(O)c1cccnc1.Oc1ccccc1

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.81
ALDH1A1 P00352 2/20 0.81
APP P05067 1/20 0.81
HCAR3 P49019 1/20 0.81
HCAR2 Q8TDS4 1/20 0.81
PLOD2 O00469 1/20 0.58
F7 P08709 1/20 0.55
F3 P13726 1/20 0.55
SARM1 Q6SZW1 1/20 0.55
SIRT2 Q8IXJ6 1/20 0.55
SIRT6 Q8N6T7 1/20 0.55
SIRT1 Q96EB6 1/20 0.55
SIRT3 Q9NTG7 1/20 0.55
SIRT5 Q9NXA8 1/20 0.55
SIRT4 Q9Y6E7 1/20 0.55
KMO O15229 1/20 0.54
LMNA P02545 1/20 0.54
KMT2A Q03164 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
MKNK1 Q9BUB5 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid SCHEMBL1008425 0.90 ALDH1A1 (0.91) GAAALDH1A1APPHCAR3HCAR2
Niacin SCHEMBL150011 0.90 ALDH1A1 (1.00) GAAALDH1A1APPHCAR3HCAR2
Niacin SCHEMBL30844065 0.90
Niacin SCHEMBL29396199 0.90 ALDH1A1 (1.00) GAAALDH1A1APPHCAR3HCAR2
Niacin SCHEMBL1433 0.90
Niacin SCHEMBL28292236 0.90 ALDH1A1 (1.00) GAAALDH1A1APPHCAR3HCAR2
Niacin SCHEMBL3081560 0.90 ALDH1A1 (1.00) GAAALDH1A1APPHCAR3HCAR2
Niacin SCHEMBL29349574 0.90
Benzoic Acid SCHEMBL28211440 0.89 ALDH1A1 (0.68) GAAALDH1A1APPHCAR3HCAR2
Niacin SCHEMBL25235888 0.88 ALDH1A1 (0.95) GAAALDH1A1APPHCAR3HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109068712-A Carotenoid balances improver in blood 格力高营养食品株式会社 2018-12-21 CN disclosed
CN-108542821-A Pregnant line remediation composition and application 佛山市芊茹化妆品有限公司 2018-09-18 CN disclosed
CN-108137813-A Cured silicone particle and the beauty treatment material for wherein combining cured silicone particle 道康宁东丽株式会社 2018-06-08 CN disclosed
CN-108078893-A A kind of anti-aging eye cream 黄旭东 2018-05-29 CN disclosed
CN-107922307-A Method for producing highly unsaturated fatty acid with high purity and high yield 备前化成株式会社 2018-04-17 CN disclosed
CN-107635543-A Multi-component product and multi-step regimen for improving the appearance or feel of human skin 宝洁公司 2018-01-26 CN disclosed
CN-107209173-A For the method for the unique nutritional need for determining patient 雀巢产品技术援助有限公司 2017-09-26 CN disclosed
CN-107148261-A Method of improving the appearance of skin 宝洁公司 2017-09-08 CN disclosed
CN-107072886-A Kit for improving the appearance of skin 宝洁公司 2017-08-18 CN disclosed
CN-103242487-B Surface modifying method and surface modified elastic body 住友橡胶工业株式会社 2017-08-08 CN disclosed
CN-103096734-B nutritional composition MJN 美国控股有限责任公司 2017-08-08 CN disclosed
CN-103099800-B External application containing tranexamic acid and interior take composition 日本乐敦制药株式会社 2017-08-04 CN disclosed
CN-102858940-B Delivery particles 宝洁公司 2017-05-03 CN disclosed
CN-106456484-A External preparation 乐敦制药株式会社 2017-02-22 CN disclosed
CN-106456702-A Combination of tetrapeptides and glycerides for the treatment of androgenetic alopecia 皮埃尔·法布尔皮肤化妆品公司 2017-02-22 CN disclosed
CN-104001427-B Blood treatment hollow-fibre membrane, blood purification and manufacture method thereof 旭化成医疗株式会社 2016-11-09 CN disclosed
CN-103589530-B Delivery of particles 宝洁公司 2016-08-24 CN disclosed
CN-102858944-B Delivery of particles 宝洁公司 2016-08-24 CN disclosed
CN-105592846-A Compositions and methods for treating non-alcoholic steatohepatitis MOCHIDA PHARM CO LTD 2016-05-18 CN disclosed