SCHEMBL28069848

SCHEMBL28069848

NCc1ccc(-c2cccc(OB(O)O)c2)cc1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 5/20 0.50
MAOB P27338 4/20 0.50
HRH3 Q9Y5N1 1/20 0.47
CYP2A6 P11509 1/20 0.41
CFD P00746 1/20 0.40
F11 P03951 1/20 0.39
ST14 Q9Y5Y6 1/20 0.39
HDAC1 Q13547 1/20 0.39
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38
SLC13A5 Q86YT5 1/20 0.37
FGFR2 P21802 1/20 0.37
FGFR3 P22607 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28049619 0.84 MGLL (0.48) HDAC1RXRARXRB
SCHEMBL28069904 0.84 HRH3 (0.56) TAAR1MAOBHRH3CYP2A6F11
SCHEMBL27569009 0.82 ENPP2 (0.48) TAAR1MAOBF11ST14
SCHEMBL29643534 0.82 ENPP2 (0.48) TAAR1MAOBF11ST14
SCHEMBL30683339 0.82 MGLL (0.50) HDAC1RXRARXRB
SCHEMBL1942125 0.82 MGLL (0.50) HDAC1RXRARXRB
Hydrochloric Acid SCHEMBL28156681 0.81 ENPP2 (0.47) TAAR1MAOBF11
SCHEMBL8672186 0.80 MGLL (0.48) HDAC1RXRARXRB
SCHEMBL29209615 0.80 MGLL (0.48) CYP2A6HDAC1RXRARXRB
SCHEMBL3591237 0.78 ST14 (0.50) MAOBHRH3F11ST14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103570620-B The luxuriant and rich with fragrance compounds of a kind of 1,12-imino group benzo [c], intermediate and preparation method and application 昆山维信诺显示技术有限公司 2016-06-15 CN disclosed