Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27951530 | 0.84 | MAPT (0.48) | LMNASMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL12502625 | 0.84 | TSHR (0.54) | LMNASMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL28829407 | 0.78 | GSK3A (0.41) | NOTUMLMNASMN1; SMN2TSHRMEN1 | |
| SCHEMBL3001518 | 0.75 | GSK3B (0.52) | NOTUMLMNASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL12502788 | 0.72 | TSHR (0.51) | LMNASMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL182646 | 0.72 | FOLH1 (0.49) | NOTUMLMNASMN1; SMN2TSHRMEN1 | |
| SCHEMBL28841921 | 0.72 | CCR2 (0.49) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL289221 | 0.71 | CAPN1 (0.54) | NOTUMLMNASMN1; SMN2TSHRMEN1 | |
| SCHEMBL23660840 | 0.70 | KMT2A (0.51) | NOTUMLMNASMN1; SMN2TSHRMEN1 | |
| SCHEMBL17625299 | 0.70 | FOLH1 (0.62) | LMNASMN1; SMN2MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103608346-B | As the 7-naphthyridine derivatives of hypoxia inducible factor (HIF) hydroxylase inhibitors | 菲布罗根有限公司 | 2016-06-15 | — | — | CN | disclosed |