Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.54 |
| ▸ | CCR2 | P41597 | 4/20 | 0.53 |
| ▸ | GSK3A | P49840 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12584121 | 0.88 | CCR2 (0.55) | CAPN1CCR2POLBSMN1; SMN2LMNA | |
| SCHEMBL28020981 | 0.86 | CAPN1 (0.59) | CAPN1CCR2GSK3AGSK3BTSHR | |
| SCHEMBL28447829 | 0.83 | IDH1 (0.46) | CCR2GSK3AGSK3BTSHRPOLB | |
| SCHEMBL289069 | 0.81 | CAPN1 (0.51) | CAPN1GSK3AGSK3BTSHRPOLB | |
| SCHEMBL17477638 | 0.78 | GPR35 (0.41) | CAPN1TSHRPOLBHSD17B10GPR35 | |
| SCHEMBL12391301 | 0.76 | GPR35 (0.51) | GSK3AGSK3BPOLBGPR35SMN1; SMN2 | |
| SCHEMBL14229126 | 0.76 | CCR2 (0.58) | CCR2GSK3AGSK3BTSHRPOLB | |
| SCHEMBL29264842 | 0.76 | GSK3A (0.52) | GSK3AGSK3BHSD17B10SMN1; SMN2LMNA | |
| SCHEMBL15079330 | 0.76 | CCR2 (0.51) | CCR2ALDH1A1 | |
| SCHEMBL17477618 | 0.75 | HPGD (0.41) | CAPN1POLBLMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3174852-B1 | ARYLHYDRAZIDES CONTAINING A 2-PYRIDONE MOIETY AS SELECTIVE ANTIBACTERIAL AGENTS | ABAC THERAPEUTICS S L (ES) | 2018-07-18 | — | — | EP | claimed |
| US-9840467-B2 | Arylhydrazides containing a 2-pyridone moiety as selective antibacterial agents | ABAC Therapeutics, S.L. (ES) | 2017-12-12 | — | — | US | claimed |
| US-20170217887-A1 | ARYLHYDRAZIDES CONTAINING A 2-PYRIDONE MOIETY AS SELECTIVE ANTIBACTERIAL AGENTS | ABAC Therapeutics, S.L. (ES) | 2017-08-03 | — | — | US | claimed |
| EP-3174852-A1 | ARYLHYDRAZIDES CONTAINING A 2-PYRIDONE MOIETY AS SELECTIVE ANTIBACTERIAL AGENTS | ABAC THERAPEUTICS, S.L. (ES) | 2017-06-07 | — | — | EP | claimed |
| CN-106660962-A | Arylhydrazides containing 2-pyridone moieties for use as selective antibacterial agents | ABAC治疗法有限公司 | 2017-05-10 | — | — | CN | claimed |
| WO-2016016291-A1 | ARYLHYDRAZIDES CONTAINING A 2-PYRIDONE MOIETY AS SELECTIVE ANTIBACTERIAL AGENTS | FERRER INTERNACIONAL, S.A. (ES) | 2016-02-04 | — | — | WO | claimed |
| EP-3174852-B1 | ARYLHYDRAZIDES CONTAINING A 2-PYRIDONE MOIETY AS SELECTIVE ANTIBACTERIAL AGENTS | ABAC THERAPEUTICS S L (ES) | 2018-07-18 | — | — | EP | disclosed |
| US-9840467-B2 | Arylhydrazides containing a 2-pyridone moiety as selective antibacterial agents | ABAC Therapeutics, S.L. (ES) | 2017-12-12 | — | — | US | disclosed |
| US-20170217887-A1 | ARYLHYDRAZIDES CONTAINING A 2-PYRIDONE MOIETY AS SELECTIVE ANTIBACTERIAL AGENTS | ABAC Therapeutics, S.L. (ES) | 2017-08-03 | — | — | US | disclosed |
| EP-3174852-A1 | ARYLHYDRAZIDES CONTAINING A 2-PYRIDONE MOIETY AS SELECTIVE ANTIBACTERIAL AGENTS | ABAC THERAPEUTICS, S.L. (ES) | 2017-06-07 | — | — | EP | disclosed |
| CN-106660962-A | Arylhydrazides containing 2-pyridone moieties for use as selective antibacterial agents | ABAC治疗法有限公司 | 2017-05-10 | — | — | CN | disclosed |
| EP-2427429-B1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS | ABBVIE DEUTSCHLAND (DE) | 2017-02-15 | — | — | EP | disclosed |
| US-9527811-B2 | Carboxamide compounds and their use as calpain inhibitors | AbbVie Deutschland GmbH & Co. KG (DE) | 2016-12-27 | — | — | US | disclosed |
| US-8283363-B2 | Carboxamide compounds and their use as calpain inhibitors | ABBOTT LABORATORIES (US) | 2012-10-09 | — | — | US | disclosed |
| US-8236798-B2 | Carboxamide compounds and their use as calpain inhibitors | ABBOTT GMBH & CO. KG (DE) | 2012-08-07 | — | — | US | disclosed |
| EP-2427429-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS | Abbott GmbH & Co. KG (DE) | 2012-03-14 | — | — | EP | disclosed |
| US-20110086879-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS | ABBOTT GMBH & CO. KG (DE) | 2011-04-14 | — | — | US | disclosed |
| WO-2010128102-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS | ABBOTT GMBH & CO. KG (DE) | 2010-11-11 | — | — | WO | disclosed |
| US-20100286146-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS | ABBOTT GMBH & CO. KG (DE) | 2010-11-11 | — | — | US | disclosed |
| US-20080188528-A1 | Modulators of C3a receptor and methods of use thereof | ENCYSIVE PHARMACEUTICALS, INC. | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286146-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS | CAPN1, CAPN2, CAPNS1 | CAPN1 1/4885CCR2 3474/4885GSK3A 712/4885 |
| US-20080188528-A1 | Modulators of C3a receptor and methods of use thereof | C3AR1, C5, C5AR1 | CAPN1 1201/4885CCR2 368/4885GSK3A 2650/4885 |
| US-20110086879-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS | CAPN1, CAPN2, CAPNS1 | CAPN1 1/4885CCR2 3474/4885GSK3A 712/4885 |
| US-20170217887-A1 | ARYLHYDRAZIDES CONTAINING A 2-PYRIDONE MOIETY AS SELECTIVE ANTIBACTERIAL AGENTS | ABCC5, AAAS, PDXK | CAPN1 4389/4885CCR2 393/4885GSK3A 2671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.