SCHEMBL2806992

SCHEMBL2806992

CCCCCCC#Cc1ccc2cc(C(=O)O)ccc2c1

nearest known ligand 0.59

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.59
MMP12 P39900 1/20 0.59
FFAR1 O14842 1/20 0.53
FFAR4 Q5NUL3 1/20 0.53
TP53 P04637 1/20 0.51
TSHR P16473 1/20 0.51
PLA2G4B P0C869 5/20 0.50
RARB P10826 3/20 0.48
PLA2G4A P47712 1/20 0.46
PLA2G2A P14555 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6937097 1.00 MMP2 (0.59) MMP2MMP12FFAR1FFAR4TP53
SCHEMBL7337990 0.99 MMP2 (0.56) MMP2MMP12FFAR1FFAR4TP53
SCHEMBL181321 0.86 MMP2 (0.52) MMP2MMP12FFAR1FFAR4
SCHEMBL30143434 0.86 MMP2 (0.72) MMP2MMP12FFAR1FFAR4TP53
SCHEMBL4271492 0.86 MMP2 (0.72) MMP2MMP12FFAR1FFAR4TP53
SCHEMBL6934491 0.86 MMP2 (0.72) MMP2MMP12FFAR1FFAR4TP53
SCHEMBL6934714 0.85 MMP2 (0.51) MMP2MMP12FFAR1FFAR4
SCHEMBL7330109 0.84 MMP2 (0.50) MMP2MMP12FFAR1FFAR4
SCHEMBL6937361 0.84 MMP2 (0.69) MMP2MMP12FFAR1FFAR4TP53
SCHEMBL6936308 0.82 MMP2 (0.67) MMP2MMP12FFAR1FFAR4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010098372-A1 FIELD EFFECT TRANSISTOR 国立大学法人広島大学 (JP) 2010-09-02 WO disclosed