Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP12 | P39900 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 2/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL181321 | 0.99 | MMP2 (0.52) | MMP2MMP12FFAR1FFAR4MGLL | |
| SCHEMBL7341769 | 0.96 | MMP2 (0.45) | MMP2MMP12MGLLPTPN11PTPN2 | |
| SCHEMBL6934714 | 0.88 | MMP2 (0.51) | MMP2MMP12FFAR1FFAR4PTPN11 | |
| SCHEMBL7337990 | 0.85 | MMP2 (0.56) | MMP2MMP12FFAR1FFAR4 | |
| SCHEMBL2806992 | 0.84 | MMP2 (0.59) | MMP2MMP12FFAR1FFAR4 | |
| SCHEMBL6937097 | 0.84 | MMP2 (0.59) | MMP2MMP12FFAR1FFAR4 | |
| SCHEMBL2402609 | 0.82 | MMP2 (0.59) | MMP2MMP12FFAR1FFAR4MGLL | |
| SCHEMBL22264120 | 0.81 | MMP2 (0.48) | MMP2MMP12FFAR1FFAR4MGLL | |
| SCHEMBL16486830 | 0.80 | MMP2 (0.50) | MMP2MMP12FFAR1FFAR4MGLL | |
| SCHEMBL19513816 | 0.78 | PTPN11 (0.51) | PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788511-B1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-12-11 | — | — | EP | disclosed |
| US-6265536-B1 | MICROBIOCIDE AND FUNGICIDE WHICH IS INHIBITOR OF BETA-1,3-GLUCAN SYNTHASE; TREATMENT OF PNEUMOCYSTIS CARINII INFECTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| US-6107458-A | FUNGICIDE WHICH IS BETA-1,3-GLYCAN SYNTHASE INHIBITOR; FOR PROPHYLAXIS AND TREATMENT OF PNEUMOCYSTIS CARINII INFECTIONS LIKE PNEUMONIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-08-22 | — | — | US | disclosed |
| EP-0788511-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |
| WO-1996011210-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-18 | — | — | WO | disclosed |