Formamide

Formamide

SCHEMBL28069980

CNNC(=O)CO.NC=O

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.43
KDM5C P41229 1/20 0.43
EGLN1 Q9GZT9 1/20 0.43
PHF8 Q9UPP1 1/20 0.43
KDM2A Q9Y2K7 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6773592 0.87
SCHEMBL12725535 0.71
SCHEMBL2500295 0.70 KDM4E (0.57) KDM4EKDM5CEGLN1PHF8KDM2A
SCHEMBL7108066 0.69 OR51E2 (0.33)
Formamide SCHEMBL28255733 0.68
Formamide SCHEMBL11769330 0.68 MGAM (0.43) KDM4EKDM5CEGLN1PHF8KDM2A
SCHEMBL16204454 0.67
SCHEMBL15499757 0.67
Formamide SCHEMBL28160645 0.67 GAA (0.36) KDM4E
Formamide SCHEMBL28155924 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105793240-A Process for making reverse transcriptase inhibitors 默沙东公司 2016-07-20 CN disclosed