⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL28069980 | 0.87 | KDM4E (0.43) | — | |
| SCHEMBL2500295 | 0.80 | KDM4E (0.57) | — | |
| SCHEMBL7108066 | 0.79 | OR51E2 (0.33) | — | |
| SCHEMBL15499757 | 0.77 | — | — | |
| SCHEMBL16204454 | 0.77 | — | — | |
| SCHEMBL18576296 | 0.75 | — | — | |
| SCHEMBL12725535 | 0.75 | — | — | |
| SCHEMBL2242250 | 0.75 | — | — | |
| SCHEMBL15778117 | 0.75 | MCL1 (0.32) | — | |
| SCHEMBL96318 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11312721-B2 | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment | AGENEBIO, INC. (US) | 2022-04-26 | — | — | US | disclosed |
| US-20210009602-A1 | BENZODIAZEPINE DERIVATIVES, COMPOSITIONS, AND METHODS FOR TREATING COGNITIVE IMPAIRMENT | HAGER BIOSCIENCES | 2021-01-14 | — | — | US | disclosed |
| EP-2709609-B1 | HETEROCYCLIC COMPOUNDS | SHIONOGI & CO (JP) | 2017-10-04 | — | — | EP | disclosed |
| US-9676726-B2 | Process for the regioselective synthesis of pyrazoles | ISAGRO S.P.A. (IT) | 2017-06-13 | — | — | US | disclosed |
| EP-3156410-A1 | POLYENE MACROLIDE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2017-04-19 | — | — | EP | disclosed |
| US-20160318874-A1 | PROCESS FOR THE REGIOSELECTIVE SYNTHESIS OF PYRAZOLES | FMC IP TECHNOLOGY GMBH (CH) | 2016-11-03 | — | — | US | disclosed |
| CN-105793240-A | Process for making reverse transcriptase inhibitors | 默沙东公司 | 2016-07-20 | — | — | CN | disclosed |
| CN-104994855-A | Process for making reverse transcriptase inhibitors | MERCK SHARP & DOHME | 2015-10-21 | — | — | CN | disclosed |
| US-20040167193-A1 | Difluoromethyltriazolone compounds, use of the same and intermediates for the production thereof | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-08-26 | — | — | US | disclosed |
| US-6762197-B2 | FUNGICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-07-13 | — | — | US | disclosed |
| US-20030119670-A1 | Difluoromethyltriazolone compounds, use of the same and intermediates for the production thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-06-26 | — | — | US | disclosed |
| EP-1238975-A1 | DIFLUOROMETHYLTRIAZOLONE COMPOUNDS, USE OF THE SAME AND INTERMEDIATES FOR THE PRODUCTION THEREOF | Sumitomo Chemical Company, Limited (JP) | 2002-09-11 | — | — | EP | disclosed |