Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | DAGLA | Q9Y4D2 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ABHD11 | Q8NFV4 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12606498 | 0.86 | KMT2A (0.51) | KMT2AMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL1198628 | 0.86 | NPC1 (0.52) | KMT2AMAPTALDH1A1KDM4EDAGLA | |
| SCHEMBL20910819 | 0.84 | ALDH1A1 (0.55) | KMT2AMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL14413594 | 0.84 | KMT2A (0.50) | KMT2AMAPTALDH1A1KDM4EDAGLA | |
| SCHEMBL19917089 | 0.84 | KMT2A (0.50) | KMT2AMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL7762330 | 0.82 | L3MBTL1 (0.53) | KMT2AMAPTALDH1A1KDM4EDAGLA | |
| SCHEMBL988939 | 0.82 | KMT2A (0.53) | KMT2AMAPTALDH1A1KDM4EDAGLA | |
| SCHEMBL7194304 | 0.82 | KMT2A (0.53) | KMT2AMAPTALDH1A1KDM4EDAGLA | |
| SCHEMBL10667417 | 0.82 | ALDH1A1 (0.54) | KMT2AMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL13198897 | 0.81 | KMT2A (0.51) | KMT2AMAPTALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105753768-A | Production method of single nitrogenous heterocyclic ring-containing compound | 北京恒瑞新霖科技有限公司 | 2016-07-13 | — | — | CN | disclosed |