SCHEMBL28070432

SCHEMBL28070432

CCC(=O)c1ccc(S(C)(=O)=O)cc1Cl

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.54
AVPR2 P30518 1/20 0.48
GPR27 Q9NS67 1/20 0.48
ALDH1A1 P00352 3/20 0.47
MEN1 O00255 1/20 0.47
CYP2C19 P33261 1/20 0.47
PPARG P37231 1/20 0.47
KMT2A Q03164 1/20 0.47
NCOA2 Q15596 1/20 0.47
NCOA1 Q15788 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
RXFP1 Q9HBX9 1/20 0.47
MAPT P10636 4/20 0.47
THRB P10828 1/20 0.46
GAA P10253 1/20 0.46
RAB9A P51151 1/20 0.46
SMO Q99835 1/20 0.45
USP28 Q96RU2 7/20 0.44
HSP90AB1 P08238 1/20 0.42
MAPK1 P28482 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8608459 0.88 LMNA (0.49) LMNAAVPR2GPR27ALDH1A1MEN1
SCHEMBL16586878 0.85 LMNA (0.53) LMNAAVPR2GPR27ALDH1A1MEN1
SCHEMBL8488393 0.84 LMNA (0.51) LMNAAVPR2GPR27ALDH1A1MEN1
SCHEMBL8489320 0.81 LMNA (0.49) LMNAAVPR2GPR27ALDH1A1MEN1
SCHEMBL27851563 0.81 HSP90AB1 (0.61) LMNAALDH1A1MEN1KMT2ARAB9A
SCHEMBL2204507 0.81 MEN1 (0.47) LMNAAVPR2GPR27ALDH1A1MEN1
SCHEMBL403618 0.81 LMNA (0.74) LMNAAVPR2GPR27ALDH1A1MEN1
SCHEMBL1016807 0.81 LMNA (0.59) LMNAAVPR2GPR27ALDH1A1MEN1
SCHEMBL12724094 0.81 LMNA (0.59) LMNAAVPR2GPR27ALDH1A1MEN1
SCHEMBL27341081 0.80 LMNA (0.42) LMNAALDH1A1MAPTRAB9AHSP90AB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105682465-A Agricultural chemicals 瑞戴格作物保护公司 2016-06-15 CN disclosed