Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.47 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMO | Q99835 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | USP28 | Q96RU2 | 7/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28070432 | 0.88 | LMNA (0.54) | LMNAAVPR2GPR27ALDH1A1MEN1 | |
| SCHEMBL8488393 | 0.85 | LMNA (0.51) | LMNAAVPR2GPR27ALDH1A1MEN1 | |
| SCHEMBL8489320 | 0.82 | LMNA (0.49) | LMNAAVPR2GPR27ALDH1A1MEN1 | |
| SCHEMBL2204507 | 0.82 | MEN1 (0.47) | LMNAAVPR2GPR27ALDH1A1MEN1 | |
| SCHEMBL16586878 | 0.80 | LMNA (0.53) | LMNAAVPR2GPR27ALDH1A1MEN1 | |
| SCHEMBL1016807 | 0.76 | LMNA (0.59) | LMNAAVPR2GPR27ALDH1A1MEN1 | |
| SCHEMBL12724094 | 0.76 | LMNA (0.59) | LMNAAVPR2GPR27ALDH1A1MEN1 | |
| SCHEMBL403618 | 0.76 | LMNA (0.74) | LMNAAVPR2GPR27ALDH1A1MEN1 | |
| SCHEMBL1258694 | 0.75 | LMNA (0.54) | LMNAAVPR2GPR27ALDH1A1MEN1 | |
| SCHEMBL26412112 | 0.75 | AVPR2 (0.58) | LMNAAVPR2GPR27ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804532-A | REACTING A BENZOYL ISOXAZOLE WITH A BASE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1998-09-08 | — | — | US | disclosed |