Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TACR3 | P29371 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27776890 | 0.82 | CES2 (0.39) | CES2CES1MEN1KMT2ACYP3A4 | |
| SCHEMBL27817482 | 0.82 | CES2 (0.39) | CES2CES1MEN1KMT2ACYP3A4 | |
| SCHEMBL1155728 | 0.77 | CES2 (0.43) | CES2CES1MEN1KMT2ACYP3A4 | |
| SCHEMBL28207484 | 0.75 | CES2 (0.39) | CES2CES1MEN1KMT2ACYP3A4 | |
| SCHEMBL11602791 | 0.75 | CES2 (0.54) | CES2CES1MEN1KMT2ACYP3A4 | |
| SCHEMBL5485147 | 0.74 | PDE2A (0.54) | CES2CES1MEN1KMT2ACYP3A4 | |
| SCHEMBL29591877 | 0.74 | PDE2A (0.54) | CES2CES1MEN1KMT2ACYP3A4 | |
| SCHEMBL27881361 | 0.73 | MEN1 (0.38) | CES2CES1MEN1KMT2ACYP3A4 | |
| SCHEMBL2775190 | 0.71 | CES2 (0.41) | CES2CES1MEN1KMT2ACYP3A4 | |
| SCHEMBL9437111 | 0.71 | KMT2A (0.47) | CES2CES1MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105669699-A | Preparation method of prasugrel hydrochloride | 山东罗欣药业集团股份有限公司 | 2016-06-15 | — | — | CN | claimed |
| CN-105669699-B | A kind of preparation method of prasugrel hydrochloride | 山东罗欣药业集团股份有限公司 | 2018-03-06 | — | — | CN | disclosed |
| CN-105669699-A | Preparation method of prasugrel hydrochloride | 山东罗欣药业集团股份有限公司 | 2016-06-15 | — | — | CN | disclosed |