Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TACR3 | P29371 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27817485 | 0.81 | MAPT (0.39) | CES2CES1CYP3A4MEN1KMT2A | |
| SCHEMBL27776891 | 0.81 | MAPT (0.39) | CES2CES1CYP3A4MEN1KMT2A | |
| SCHEMBL1155729 | 0.76 | MEN1 (0.42) | CES2CES1CYP3A4MEN1KMT2A | |
| SCHEMBL28070537 | 0.75 | CES2 (0.44) | CES2CES1CYP3A4MEN1KMT2A | |
| SCHEMBL11602791 | 0.74 | CES2 (0.54) | CES2CES1CYP3A4MEN1KMT2A | |
| SCHEMBL5485147 | 0.73 | PDE2A (0.54) | CES2CES1CYP3A4MEN1KMT2A | |
| SCHEMBL29591877 | 0.73 | PDE2A (0.54) | CES2CES1CYP3A4MEN1KMT2A | |
| SCHEMBL8593461 | 0.71 | CES2 (0.48) | CES2CES1CYP3A4MEN1KMT2A | |
| SCHEMBL9437113 | 0.70 | KMT2A (0.38) | CES2CES1CYP3A4MEN1KMT2A | |
| SCHEMBL1155728 | 0.69 | CES2 (0.43) | CES2CES1CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105669699-B | A kind of preparation method of prasugrel hydrochloride | 山东罗欣药业集团股份有限公司 | 2018-03-06 | — | — | CN | disclosed |