Paraben

Paraben

SCHEMBL28070554

C=CC(=O)OC(C)Oc1ccccc1.O=C(O)c1ccc(O)cc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.45
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA7 P43166 2/20 0.42
CA9 Q16790 2/20 0.42
CA14 Q9ULX7 2/20 0.42
CA3 P07451 1/20 0.42
TYR P14679 1/20 0.42
DRD1 P21728 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
SRD5A2 P31213 5/20 0.40
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
ALDH5A1 P51649 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7797255 0.89 KMT2A (0.57) KMT2ACA1CA2RXRARXRB
Phenol SCHEMBL28077940 0.88 THRB (0.40) KMT2ACA12CA1CA2CA7
SCHEMBL34034 0.87 THRB (0.46) KMT2APKMALDH1A1THRBTSHR
Water SCHEMBL28126876 0.86 THRB (0.45) KMT2APKMALDH1A1THRBTSHR
SCHEMBL9771285 0.86 CA12 (0.41) KMT2ACA12CA1CA2CA7
Acrylic Acid SCHEMBL7185233 0.84 THRB (0.44) KMT2APKMALDH1A1THRBTSHR
Acrylic Acid SCHEMBL28252917 0.84 THRB (0.44) KMT2APKMALDH1A1THRBTSHR
SCHEMBL28010865 0.83 THRB (0.43) KMT2APKMALDH1A1THRB
SCHEMBL2402189 0.82 ELANE (0.50) KMT2ASRD5A2ALDH1A1
Ethylene Glycol SCHEMBL7182341 0.82 THRB (0.45) KMT2APKMALDH1A1THRBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101442908-B The tick of preparation and insect repellent composition 纳幕尔杜邦公司 2016-09-28 CN disclosed