SCHEMBL7797255

SCHEMBL7797255

C=CC(=O)OC(C)Oc1ccc(C(=O)O)cc1

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.57
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
MAPK1 P28482 1/20 0.43
SRD5A2 P31213 2/20 0.42
ALDH1A1 P00352 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
RXRA P19793 3/20 0.40
RXRB P28702 2/20 0.40
PARP10 Q53GL7 2/20 0.40
PLA2G4B P0C869 1/20 0.40
HSD17B10 Q99714 1/20 0.39
RARB P10826 1/20 0.38
HTT P42858 1/20 0.38
PARP15 Q460N3 1/20 0.38
TP53 P04637 1/20 0.38
TSHR P16473 1/20 0.38
XDH P47989 1/20 0.37
HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Paraben SCHEMBL28070554 0.89 KMT2A (0.45) KMT2ACA1CA2SRD5A2ALDH1A1
SCHEMBL11966996 0.88 MAPT (0.46) KMT2AALDH1A1L3MBTL1PARP10HTT
SCHEMBL2402189 0.87 ELANE (0.50) KMT2AMAPK1SRD5A2ALDH1A1L3MBTL1
SCHEMBL34034 0.85 THRB (0.46) KMT2AMAPK1ALDH1A1TP53TSHR
SCHEMBL13296348 0.85 CYP1A2 (0.45) KMT2APARP10HSD17B10TSHR
SCHEMBL10870942 0.85 THRB (0.50) KMT2AALDH1A1PARP10TP53TSHR
Water SCHEMBL28126876 0.84 THRB (0.45) KMT2AMAPK1ALDH1A1TP53TSHR
SCHEMBL9771285 0.84 CA12 (0.41) KMT2ACA1CA2ALDH1A1PARP10
SCHEMBL13368777 0.84 PARP10 (0.39) KMT2AALDH1A1PARP10HTTTSHR
SCHEMBL9488041 0.84 KMT2A (0.41) KMT2AALDH1A1L3MBTL1PARP10HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6248259-B1 OPTICAL ELEMENT SHOWING CIRCULAR DICHROISM IN THE VISIBLE WAVELENGTH REGION COMPRISING SOLID LAYER OF CHOLESTERIC LIQUID CRYSTAL PHASE; IMPROVED MOLECULAR ORIENTATION, DURABILITY, HEAT RESISTANCE NITTO DENKO CORPORATION (JP) 2001-06-19 US disclosed
US-20010003359-A1 Optically active monomer, liquid crystal polymer, and optical element IZUMI KYOKO (JP) 2001-06-14 US disclosed
EP-1055721-A2 Liquid crystal polymer composition, oriented film and process for producing the film NITTO DENKO CORPORATION (JP) 2000-11-29 EP disclosed
EP-0980868-A1 OPTICALLY ACTIVE MONOMER, LIQUID CRYSTALLINE POLYMER, AND OPTICAL ELEMENT Nitto Denko Corporation (JP) 2000-02-23 EP disclosed
EP-0007574-B1 LIQUID-CRYSTALLINE POLYMERIC PHASE WITH A CHOLESTERIC STRUCTURE, METHOD FOR ITS PREPARATION AND ITS USE BASF Aktiengesellschaft (DE) 1983-05-25 EP disclosed
US-4293435-A ACRYLATE POLYMERS BASF AKTIENGESELLSCHAFT (DE) 1981-10-06 US disclosed
EP-0007574-A1 Liquid-crystalline polymeric phase with a cholesteric structure, method for its preparation and its use BASF Aktiengesellschaft (DE) 1980-02-06 EP disclosed