Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SOD1 | P00441 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 3/20 | 0.49 |
| ▸ | DRD5 | P21918 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1646170 | 0.87 | POLB (0.67) | POLBKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL10359671 | 0.80 | KCNJ1 (0.82) | POLBSIRT6HTR1AKCNJ1KCNH2 | |
| SCHEMBL11624093 | 0.78 | HTR1A (0.55) | POLBKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL1644607 | 0.78 | HTR1A (0.54) | POLBKMT2AMAPTSIRT6HTR1A | |
| SCHEMBL12431530 | 0.77 | MAPT (0.70) | POLBKMT2AALDH1A1MAPTSIRT6 | |
| SCHEMBL12610815 | 0.76 | KCNJ1 (0.75) | ALDH1A1MAPTSMN1; SMN2HTR1AKCNJ1 | |
| SCHEMBL27977424 | 0.76 | SIRT6 (0.60) | POLBKMT2AALDH1A1MAPTSIRT6 | |
| SCHEMBL4248033 | 0.76 | SIRT6 (0.64) | POLBKMT2AALDH1A1MAPTSIRT6 | |
| SCHEMBL15599506 | 0.76 | POLB (0.64) | POLBKMT2AALDH1A1MAPTSIRT6 | |
| SCHEMBL4628534 | 0.76 | SIRT6 (0.64) | POLBKMT2AALDH1A1MAPTSIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105541702-A | Arylamine alkyl sulfide compound with structure similar to ruzadolane and preparation method of compound | UNIV YICHUN | 2016-05-04 | — | — | CN | disclosed |