Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GRM8 | O00222 | 2/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | GRM6 | O15303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28070806 | 1.00 | GRM4 (0.37) | GRM4ALDH1A1GRM8MMP13ITGA4 | |
| SCHEMBL28905368 | 0.86 | ALDH1A1 (0.39) | GRM4ALDH1A1GRM8MMP13PDCD1 | |
| SCHEMBL15414331 | 0.86 | ALDH1A1 (0.39) | GRM4ALDH1A1GRM8MMP13PDCD1 | |
| SCHEMBL15432849 | 0.86 | ALDH1A1 (0.39) | GRM4ALDH1A1GRM8MMP13PDCD1 | |
| SCHEMBL15433036 | 0.85 | GRM4 (0.43) | GRM4ALDH1A1GRM8MMP13ITGA4 | |
| SCHEMBL19278903 | 0.85 | GRM4 (0.43) | GRM4ALDH1A1GRM8MMP13ITGA4 | |
| SCHEMBL18928692 | 0.84 | ALDH1A1 (0.52) | GRM4ALDH1A1GRM8GRM6 | |
| SCHEMBL7515946 | 0.84 | ALDH1A1 (0.52) | GRM4ALDH1A1GRM8GRM6 | |
| SCHEMBL28302644 | 0.83 | AAK1 (0.40) | MMP13ITGA4AAK1SLC7A5 | |
| SCHEMBL28302645 | 0.83 | AAK1 (0.40) | MMP13ITGA4AAK1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110279872-A | Conjugated body of the cytotoxic molecule with cell bound receptor molecule | 杭州多禧生物科技有限公司 | 2019-09-27 | — | — | CN | disclosed |
| CN-109912683-A | Cytotoxin molecule, conjugate, preparation method and application thereof | 杭州多禧生物科技有限公司 | 2019-06-21 | — | — | CN | disclosed |
| CN-105641707-A | Conjugates of cytotoxic molecules and cell-binding receptor molecules | 杭州多禧生物科技有限公司 | 2016-06-08 | — | — | CN | disclosed |