Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | GRM8 | O00222 | 3/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.39 |
| ▸ | GRM6 | O15303 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7515946 | 1.00 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2LMNAGAAHTT | |
| SCHEMBL28921925 | 0.91 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL28905368 | 0.88 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2GAAGRM8GRM4 | |
| SCHEMBL15432849 | 0.88 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2GAAGRM8GRM4 | |
| SCHEMBL15414331 | 0.88 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2GAAGRM8GRM4 | |
| SCHEMBL15433036 | 0.87 | GRM4 (0.43) | ALDH1A1SMN1; SMN2GRM8GRM4GRM6 | |
| SCHEMBL19278903 | 0.87 | GRM4 (0.43) | ALDH1A1SMN1; SMN2GRM8GRM4GRM6 | |
| SCHEMBL28070805 | 0.84 | GRM4 (0.37) | ALDH1A1GRM8GRM4GRM6 | |
| SCHEMBL28070806 | 0.84 | GRM4 (0.37) | ALDH1A1GRM8GRM4GRM6 | |
| SCHEMBL17035356 | 0.83 | LDHA (0.47) | ALDH1A1LMNAHTTLDHARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170157262-A1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2017-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170157262-A1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | CD4, CD2, CD47 | ALDH1A1 3672/4885SMN1; SMN2 2663/4885LMNA 2380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.