Siduron

Siduron

SCHEMBL28070889

CC1CCCCC1NC(=O)Nc1ccccc1.c1cncnc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 7/20 0.56
TAS1R1 Q7RTX1 7/20 0.56
EPHX1 P07099 4/20 0.52
EPHX2 P34913 1/20 0.52
RAB9A P51151 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
POLB P06746 1/20 0.49
P2RY1 P47900 1/20 0.47
CHRNA7 P36544 1/20 0.47
MAPT P10636 1/20 0.44
TAAR1 Q96RJ0 1/20 0.44
TAS1R2 Q8TE23 3/20 0.44
ALDH1A1 P00352 1/20 0.44
GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Siduron SCHEMBL66323 0.91 TAS1R3 (0.66) TAS1R3TAS1R1EPHX1EPHX2RAB9A
Siduron SCHEMBL4895915 0.91 TAS1R3 (0.66) TAS1R3TAS1R1EPHX1EPHX2RAB9A
Siduron SCHEMBL22188688 0.78 TAS1R3 (0.52) TAS1R3TAS1R1EPHX1EPHX2RAB9A
Siduron SCHEMBL9706942 0.76 TAS1R3 (0.53) TAS1R3TAS1R1EPHX1EPHX2RAB9A
Siduron SCHEMBL9269619 0.76 TAS1R3 (0.53) TAS1R3TAS1R1EPHX1EPHX2RAB9A
SCHEMBL17079596 0.74 NPC1 (0.70) RAB9ASMN1; SMN2POLBMAPTALDH1A1
SCHEMBL17079605 0.74 EPHX1 (0.67) TAS1R3TAS1R1EPHX1EPHX2RAB9A
SCHEMBL17079594 0.72 KMT2A (0.56) TAS1R3TAS1R1EPHX1RAB9ASMN1; SMN2
SCHEMBL702472 0.72 TAS1R3 (1.00) TAS1R3TAS1R1EPHX2RAB9ASMN1; SMN2
SCHEMBL701047 0.72 TAS1R3 (1.00) TAS1R3TAS1R1RAB9ASMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107207546-A Ligand component, correlated response product, reaction product, the hydrosilylation catalysts comprising the ligand component and the hydrosilylation curable compositions of activation, and for preparing their correlation technique 美国道康宁公司 2017-09-26 CN disclosed
CN-103958059-B Hydrosilylation reaction catalysts and curable compositions and methods of making and using the same 道康宁公司 2017-04-26 CN disclosed
CN-103842368-B Iridium containing hydrosilylation catalysts and compositions containing the catalysts 道康宁公司 2017-02-22 CN disclosed
CN-105764610-A Metal-containing condensation reaction catalyst, method for preparing the same, and composition comprising the same 道康宁公司 2016-07-13 CN disclosed