Siduron

Siduron

SCHEMBL9706942

CC1CCCCC1NC(=O)Nc1ccccc1.CC1CCCCC1NC(=O)Nc1ccccc1.CCNc1nc(Cl)nc(NCC)n1.CCNc1nc(Cl)nc(NCC)n1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 6/20 0.53
TAS1R1 Q7RTX1 6/20 0.53
L3MBTL1 Q9Y468 3/20 0.48
RAB9A P51151 2/20 0.48
NPC1 O15118 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2C19 P33261 1/20 0.48
SMN1; SMN2 Q16637 3/20 0.43
EPHX1 P07099 1/20 0.43
EPHX2 P34913 1/20 0.43
TAS1R2 Q8TE23 1/20 0.42
GAA P10253 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
LMNA P02545 4/20 0.41
TSHR P16473 2/20 0.40
CXCR2 P25025 1/20 0.40
CHRNA7 P36544 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Siduron SCHEMBL9269619 1.00 TAS1R3 (0.53) TAS1R3TAS1R1L3MBTL1RAB9ANPC1
Siduron SCHEMBL4895915 0.82 TAS1R3 (0.66) TAS1R3TAS1R1RAB9ASMN1; SMN2EPHX1
Siduron SCHEMBL66323 0.82 TAS1R3 (0.66) TAS1R3TAS1R1RAB9ASMN1; SMN2EPHX1
Siduron SCHEMBL28070889 0.76 TAS1R3 (0.56) TAS1R3TAS1R1RAB9ASMN1; SMN2EPHX1
Phenyl Phenylcarbamate SCHEMBL7593355 0.71 GAA (0.46) L3MBTL1RAB9ANPC1CYP1A2CYP2C19
Siduron SCHEMBL22188688 0.70 TAS1R3 (0.52) TAS1R3TAS1R1RAB9ASMN1; SMN2EPHX1
SCHEMBL702472 0.70 TAS1R3 (1.00) TAS1R3TAS1R1RAB9ANPC1CYP2C19
SCHEMBL701047 0.69 TAS1R3 (1.00) TAS1R3TAS1R1RAB9ANPC1CYP1A2
SCHEMBL12421837 0.69 MEN1 (0.73) L3MBTL1RAB9ANPC1CYP1A2CYP2C19
Siduron SCHEMBL9785480 0.67 TAS1R3 (0.51) TAS1R3TAS1R1RAB9ANPC1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992010501-A1 HERBICIDAL ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-06-25 WO disclosed
WO-1992009578-A1 SUBSTITUTED FUSED HETEROCYCLIC HERBICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-06-11 WO disclosed
EP-0457802-A1 HERBICIDAL OXABICYCLONONANE ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-11-27 EP disclosed
WO-1991015478-A1 CROP-SELECTIVE HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-10-17 WO disclosed
WO-1991003464-A1 HERBICIDAL OXABICYCLO ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-03-21 WO disclosed
WO-1990012012-A1 SUBSTITUTED PHENYLTRIAZOLOPYRIMIDINE HERBICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-18 WO disclosed
WO-1990009383-A1 HERBICIDAL OXABICYCLONONANE ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-08-23 WO disclosed