Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL913262 | 0.98 | DRD2 (0.46) | DRD2DRD3HTR1A | |
| Sulfur Dioxide SCHEMBL28071143 | 0.91 | DRD2 (0.42) | DRD2DRD3HTR1A | |
| Guanidine SCHEMBL28415570 | 0.89 | DRD2 (0.43) | DRD2DRD3HTR1A | |
| SCHEMBL27547345 | 0.81 | DRD2 (0.41) | DRD2DRD3 | |
| SCHEMBL8143198 | 0.80 | DRD2 (0.41) | DRD2DRD3 | |
| SCHEMBL17224079 | 0.79 | — | — | |
| SCHEMBL28289256 | 0.79 | — | — | |
| SCHEMBL17224077 | 0.79 | — | — | |
| SCHEMBL28648650 | 0.79 | DRD2 (0.50) | DRD2DRD3 | |
| SCHEMBL28679348 | 0.78 | DRD2 (0.43) | DRD2DRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105814025-B | Tetrahydrobenzimidazderivative derivative as TNF active regulators | UCB生物制药私人有限公司 | 2018-09-04 | — | — | CN | disclosed |
| CN-105814056-B | purine derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2017-10-10 | — | — | CN | disclosed |
| CN-105829307-A | TETRAHYDROIMIDAZOPYRIDINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB生物制药私人有限公司 | 2016-08-03 | — | — | CN | disclosed |
| CN-105814025-A | Tetrahydrobenzimidazole derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2016-07-27 | — | — | CN | disclosed |
| CN-105814065-A | Imidazothiazole derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2016-07-27 | — | — | CN | disclosed |