Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | PLK1 | P53350 | 1/20 | 0.71 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.60 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.59 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.52 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30718649 | 0.83 | ALOX15 (1.00) | ALOX15HTTPLK1HDAC1HDAC2 | |
| SCHEMBL265015 | 0.83 | ALOX15 (1.00) | ALOX15HTTPLK1HDAC1HDAC2 | |
| SCHEMBL31419202 | 0.83 | PLK1 (0.72) | ALOX15HTTPLK1HDAC1HDAC2 | |
| SCHEMBL11962154 | 0.83 | PLK1 (1.00) | ALOX15HTTPLK1HDAC1HDAC2 | |
| SCHEMBL3492806 | 0.83 | PLK1 (0.72) | ALOX15HTTPLK1HDAC1HDAC2 | |
| SCHEMBL27928930 | 0.82 | ALOX15 (0.97) | ALOX15HTTPLK1HDAC1HDAC2 | |
| SCHEMBL2575332 | 0.82 | ALOX15 (0.66) | ALOX15HTTPLK1HDAC1HDAC2 | |
| SCHEMBL2492569 | 0.81 | ALOX15 (0.73) | ALOX15HTTPLK1HDAC1HDAC2 | |
| SCHEMBL9749106 | 0.81 | PLK1 (0.73) | ALOX15HTTPLK1HDAC1HDAC2 | |
| SCHEMBL28087629 | 0.81 | MGAM (0.59) | ALOX15HTTHDAC1HDAC2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107739335-A | A kind of pleasure cuts down the synthetic method for Buddhist nun | 南京奇可药业有限公司 | 2018-02-27 | — | — | CN | disclosed |
| CN-105814040-A | Fused 1,4-dihydrodioxin derivatives as inhibitors of heat shock transcription factor 1 | 癌症研究科技有限公司 | 2016-07-27 | — | — | CN | disclosed |