Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | PLK1 | P53350 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.56 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.56 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30718649 | 1.00 | ALOX15 (1.00) | ALOX15HTTPLK1NPC1RAB9A | |
| SCHEMBL27928930 | 0.98 | ALOX15 (0.97) | ALOX15HTTPLK1NPC1RAB9A | |
| Quinoline SCHEMBL28071393 | 0.95 | ALOX15 (0.91) | ALOX15HTTPLK1NPC1RAB9A | |
| Sulfuric Acid SCHEMBL28071302 | 0.92 | ALOX15 (0.84) | ALOX15HTTPLK1NPC1RAB9A | |
| SCHEMBL18371293 | 0.88 | ALOX15 (0.78) | ALOX15HTTPLK1NPC1RAB9A | |
| SCHEMBL29893321 | 0.87 | ALOX15 (0.77) | ALOX15HTTPLK1NPC1RAB9A | |
| SCHEMBL2671065 | 0.87 | ALOX15 (0.77) | ALOX15HTTPLK1NPC1RAB9A | |
| Quinoline SCHEMBL28161564 | 0.86 | ALOX15 (0.76) | ALOX15HTTPLK1NPC1RAB9A | |
| SCHEMBL25294487 | 0.85 | HTT (0.74) | ALOX15HTTPLK1NPC1RAB9A | |
| SCHEMBL2492569 | 0.84 | ALOX15 (0.73) | ALOX15HTTPLK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 501 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117205211-B | Application of quinoline compound in preparation of fish parasitic protozoan resisting medicine | 西北农林科技大学深圳研究院 | 2024-04-05 | — | — | CN | claimed |
| CN-117205211-A | Application of quinoline compound in preparation of fish parasitic protozoan resisting medicine | 西北农林科技大学深圳研究院 | 2023-12-12 | — | — | CN | claimed |
| CN-110229102-B | 2-alkylated quinoline, derivative and synthetic method thereof | 湘潭大学 | 2022-05-17 | — | — | CN | claimed |
| CN-110229102-A | 2- is alkylated quinoline, derivative and its synthetic method | 湘潭大学 | 2019-09-13 | — | — | CN | claimed |
| US-10224485-B2 | Process for preparing a crystalline organic semiconductor material | BASF SE (DE) | 2019-03-05 | — | — | US | claimed |
| US-20170012208-A1 | ORGANIC SEMICONDUCTOR FORMULATIONS | USINVEST LLC | 2017-01-12 | — | — | US | claimed |
| EP-4745134-A1 | PROTEIN ARGINASE METHYLTRANSFERASE-5 INHIBITOR AND MEDICAL USE THEREOF | Jiangsu Yahong Meditech Co., Ltd. (CN) | 2026-05-20 | — | — | EP | disclosed |
| US-12577243-B2 | Monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2026-03-17 | — | — | US | disclosed |
| EP-3856178-B1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2026-03-11 | — | — | EP | disclosed |
| WO-2025087033-A1 | COMPOUND CONTAINING (1,3,4-THIADIAZOLE)BENZENE-1,2-ETHYLENEDIAMINE, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国海洋大学 | 2025-05-01 | — | — | WO | disclosed |
| US-12227524-B2 | Anti-infective compounds | INSTITUT PASTEUR KOREA (KR) | 2025-02-18 | — | — | US | disclosed |
| CN-119325469-A | WEE1 degrading compounds and uses thereof | 百时美施贵宝公司 | 2025-01-17 | — | — | CN | disclosed |
| CN-119285426-A | Synthesis method of diaryl acetylene | 南京工业大学 | 2025-01-10 | — | — | CN | disclosed |
| US-6284796-B1 | NAPHTHAMIDINE COMPOUNDS | ABBOTT LABORATORIES | 2001-09-04 | — | — | US | disclosed |
| CN-1268942-A | Sulfonamide compounds and medicinal use thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-10-04 | — | — | CN | disclosed |
| US-6093729-A | TREATING ARRHYTHMIAS, PROPHYLAXIS OF CARDIAC INFARCTION, ANGINA PECTORIS AND ISCHEMIC CONDITIONS OF THE HEART, SHOCK CONDITIONS, USING IN SURGICAL OPERATIONS AND ORGAN TRANSPLANTATIONS, CELL PROLIFERATION, HYPERTENSION | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-07-25 | — | — | US | disclosed |
| CN-1117045-A | Substituted bicyclic heteroaroylguanidines, a process for their preparation, their use as a medicament or a diagnostic agent, and a medicament containing them | HOECHST AG (DE) | 1996-02-21 | — | — | CN | disclosed |
| EP-0240859-B1 | LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1993-04-28 | — | — | EP | disclosed |
| US-4968803-A | FLUORINE AS OXIDANT | ALLIED-SIGNAL INC. (US) | 1990-11-06 | — | — | US | disclosed |
| CN-85100796-A | The preparation method of qualone derivative | — | 1986-10-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12577243-B2 | Monoacylglycerol lipase modulators | MGLL, LPL, FAAH | ALOX15 356/4885HTT 3651/4885PLK1 3246/4885 |
| US-12227524-B2 | Anti-infective compounds | RABGGTB, ELANE, SERPINB1 | ALOX15 1708/4885HTT 3860/4885PLK1 893/4885 |
| US-10224485-B2 | Process for preparing a crystalline organic semiconductor material | STOM, SPOP, TTR | ALOX15 4022/4885HTT 2419/4885PLK1 273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.