SCHEMBL2807113

SCHEMBL2807113

C=C(C)C(=O)OCOC[Si](OCC)(OCC)OCC

nearest known ligand 0.49

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.49
TSHR P16473 4/20 0.40
ALDH1A1 P00352 4/20 0.35
LMNA P02545 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL80190 0.85 THRB (0.50) THRBTSHRALDH1A1LMNAHSD17B10
SCHEMBL16286588 0.79 THRB (0.44) THRBTSHRALDH1A1LMNAHSD17B10
SCHEMBL36959 0.79 THRB (0.67) THRBTSHRALDH1A1LMNAHSD17B10
SCHEMBL29005374 0.79 THRB (0.47) THRBTSHRALDH1A1LMNAHSD17B10
SCHEMBL7640153 0.77 THRB (0.46) THRBTSHRALDH1A1LMNAHSD17B10
SCHEMBL16346281 0.77 THRB (0.56) THRBTSHRALDH1A1LMNAHSD17B10
SCHEMBL7638655 0.76 THRB (0.44) THRBTSHRALDH1A1LMNAHSD17B10
SCHEMBL7641737 0.76 THRB (0.44) THRBTSHRALDH1A1LMNAHSD17B10
SCHEMBL19667000 0.76 THRB (0.62) THRBTSHRALDH1A1LMNAHSD17B10
SCHEMBL260933 0.75 THRB (0.56) THRBTSHRALDH1A1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9289359-B2 Self-adhesive multicomponent dental material IVOCLAR VIVADENT AG (LI) 2016-03-22 US disclosed
EP-2233123-A1 Self-adhesive multi-component dental material Ivoclar Vivadent AG (LI) 2010-09-29 EP disclosed
US-20100240795-A1 SELF-ADHESIVE MULTICOMPONENT DENTAL MATERIAL IVOCLAR VIVADENT AG (LI) 2010-09-23 US disclosed