SCHEMBL2807120

SCHEMBL2807120

C=C(Cc1c(C)cc(C)cc1C)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 6/20 0.40
▸ POLB P06746 1/20 0.40
▸ MAPT P10636 1/20 0.40
▸ ALDH1A1 P00352 5/20 0.37
▸ SMN1; SMN2 Q16637 2/20 0.37
▸ HPGD P15428 1/20 0.37
▸ TSHR P16473 1/20 0.37
▸ TPMT P51580 1/20 0.35
▸ SLC22A12 Q96S37 1/20 0.35
▸ LMNA P02545 2/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ HTT P42858 1/20 0.33
▸ GPR17 Q13304 1/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ KMT2A Q03164 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9283073 0.80 KDM4E (0.40) KDM4EMAPTALDH1A1SMN1; SMN2HPGD
SCHEMBL509440 0.79 KDM4E (0.58) KDM4EPOLBMAPTALDH1A1HPGD
Water SCHEMBL28215001 0.77 KDM4E (0.56) KDM4EPOLBMAPTALDH1A1HPGD
Hydrochloric Acid SCHEMBL2529687 0.77 KDM4E (0.56) KDM4EPOLBMAPTALDH1A1HPGD
SCHEMBL12214120 0.76 KDM4E (0.42) KDM4EPOLBMAPTALDH1A1SMN1; SMN2
SCHEMBL1259503 0.74 KDM4E (0.41) KDM4EPOLBMAPTALDH1A1HPGD
SCHEMBL3476152 0.74 KDM4E (0.41) KDM4EPOLBMAPTALDH1A1HPGD
SCHEMBL28805333 0.72 HRH3 (0.34) KDM4EPOLBMAPTALDH1A1LMNA
SCHEMBL777612 0.72 HTT (0.45) KDM4EPOLBMAPTALDH1A1HPGD
SCHEMBL37165 0.72 KDM4E (0.40) KDM4EPOLBMAPTALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230322820-A1 BISACYL DIGERMANIUM COMPOUNDS, THEIR PREPARATION AND THEIR USE AS PHOTOINITIATOR FOR RADICAL POLYMERIZATION EVONIK OPERATIONS GMBH (DE) 2023-10-12 — — US disclosed
EP-4257592-A1 BISACYL DIGERMANIUM COMPOUNDS, THEIR PREPARATION AND THEIR USE AS PHOTOINITIATOR FOR RADICAL POLYMERIZATION Evonik Operations GmbH (DE) 2023-10-11 — — EP disclosed
US-10787468-B2 Acyl germanium photoinitiators and process for the preparation thereof IVOCLAR VIVADENT AG (LI) 2020-09-29 — — US disclosed
CN-108137727-B Acylgermanium photoinitiator and preparation method thereof 义获嘉伟瓦登特公司 2020-07-24 — — CN disclosed
US-20200087329-A1 Acyl Germanium Photoinitiators And Process For The Preparation Thereof IVOCLAR VIVADENT AG (LI) 2020-03-19 — — US disclosed
US-20180265527-A1 Acyl Germanium Photoinitiators And Process For The Preparation Thereof IVOCLAR VIVADENT AG (LI) 2018-09-20 — — US disclosed
CN-108137727-A Acyl group germanium photoinitiator and preparation method thereof 义获嘉伟瓦登特公司 2018-06-08 — — CN disclosed
US-9289359-B2 Self-adhesive multicomponent dental material IVOCLAR VIVADENT AG (LI) 2016-03-22 — — US disclosed
US-20100240795-A1 SELF-ADHESIVE MULTICOMPONENT DENTAL MATERIAL IVOCLAR VIVADENT AG (LI) 2010-09-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200087329-A1 Acyl Germanium Photoinitiators And Process For The Preparation Thereof AGPAT5, AGPAT2, GLRA2 KDM4E 480/4885POLB 990/4885MAPT 2100/4885
US-20180265527-A1 Acyl Germanium Photoinitiators And Process For The Preparation Thereof AGPAT5, AGPAT2, GLRA2 KDM4E 480/4885POLB 990/4885MAPT 2100/4885
US-10787468-B2 Acyl germanium photoinitiators and process for the preparation thereof AGPAT5, AGPAT2, GLRA2 KDM4E 480/4885POLB 990/4885MAPT 2100/4885
US-20230322820-A1 BISACYL DIGERMANIUM COMPOUNDS, THEIR PREPARATION AND THEIR USE AS PHOTOINITIATOR FOR RADICAL POLYMERIZATION GLRA3, GLRA2, CBR3 KDM4E 1600/4885POLB 1113/4885MAPT 4054/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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