Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 3/20 | 0.30 |
| ▸ | AOC1 | P19801 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6237061 | 0.78 | KMT2A (0.33) | CCNT1CDK9HASPIN | |
| SCHEMBL18341916 | 0.69 | ALDH1A1 (0.36) | PKMIDO1AOC1 | |
| SCHEMBL4541956 | 0.69 | — | — | |
| SCHEMBL4541953 | 0.69 | — | — | |
| SCHEMBL25861866 | 0.67 | ALDH1A1 (0.44) | PKMIDO1 | |
| SCHEMBL21713005 | 0.66 | CYP3A4 (0.39) | — | |
| SCHEMBL28202370 | 0.65 | ALDH1A1 (0.35) | AOC1 | |
| Hydrochloric Acid SCHEMBL28274257 | 0.62 | HRH3 (0.33) | IDO1 | |
| SCHEMBL10506714 | 0.59 | KDM4A (0.33) | IDO1 | |
| SCHEMBL20073537 | 0.58 | HPGD (0.38) | HTTHPGDRIPK1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109912599-A | Chemical entities, composition and method | 英特利凯恩有限责任公司 | 2019-06-21 | — | — | CN | disclosed |
| CN-106188059-B | Certain chemical entities, composition and method | 英特利凯恩有限责任公司 | 2019-02-01 | — | — | CN | disclosed |
| CN-103298474-B | Heterocyclic compound and application thereof | 无限药品股份有限公司 | 2016-06-29 | — | — | CN | disclosed |