Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.84 |
| ▸ | HTT | P42858 | 1/20 | 0.84 |
| ▸ | PLK1 | P53350 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.49 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL265015 | 0.92 | ALOX15 (1.00) | ALOX15HTTPLK1NPC1RAB9A | |
| SCHEMBL30718649 | 0.92 | ALOX15 (1.00) | ALOX15HTTPLK1NPC1RAB9A | |
| SCHEMBL27928930 | 0.90 | ALOX15 (0.97) | ALOX15HTTPLK1NPC1RAB9A | |
| Quinoline SCHEMBL28071393 | 0.87 | ALOX15 (0.91) | ALOX15HTTPLK1NPC1RAB9A | |
| SCHEMBL28071301 | 0.83 | ALOX15 (0.60) | ALOX15HTTPLK1NPC1RAB9A | |
| SCHEMBL18371293 | 0.81 | ALOX15 (0.78) | ALOX15HTTPLK1NPC1RAB9A | |
| SCHEMBL29893321 | 0.80 | ALOX15 (0.77) | ALOX15HTTPLK1NPC1RAB9A | |
| SCHEMBL2671065 | 0.80 | ALOX15 (0.77) | ALOX15HTTPLK1NPC1RAB9A | |
| Quinoline SCHEMBL28161564 | 0.79 | ALOX15 (0.76) | ALOX15HTTPLK1NPC1RAB9A | |
| SCHEMBL25294487 | 0.78 | HTT (0.74) | ALOX15HTTPLK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103459382-B | For suppressing the heterocyclic compound of PASK | 拜奥埃内杰尼克斯公司 | 2016-06-29 | — | — | CN | disclosed |