Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2706462 | 0.86 | PRCP (0.35) | PRCPDPP7TLR2 | |
| SCHEMBL2422874 | 0.86 | PRCP (0.35) | PRCPDPP7TLR2 | |
| SCHEMBL28911945 | 0.86 | PRCP (0.35) | PRCPDPP7TLR2 | |
| SCHEMBL333102 | 0.86 | PRCP (0.35) | PRCPDPP7TLR2 | |
| SCHEMBL675798 | 0.86 | PRCP (0.35) | PRCPDPP7TLR2 | |
| SCHEMBL11559061 | 0.85 | PRCP (0.35) | PRCPDPP7TLR2CYP1A2CYP3A4 | |
| SCHEMBL11557434 | 0.85 | REN (0.35) | PRCPDPP7TLR2CYP1A2CYP3A4 | |
| SCHEMBL11559258 | 0.83 | NOS2 (0.38) | PRCPDPP7TLR2CYP1A2CYP3A4 | |
| SCHEMBL7377621 | 0.83 | DPP7 (0.36) | PRCPDPP7TLR2CYP1A2CYP3A4 | |
| SCHEMBL11562016 | 0.82 | PRCP (0.36) | PRCPDPP7TLR2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105777712-A | Tetrahydroisoquinoline derivative and application thereof | 沈阳药科大学 | 2016-07-20 | — | — | CN | disclosed |