SCHEMBL28071870

SCHEMBL28071870

C[Si](C)(Cl)c1ccccc1F

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.40
ALDH1A1 P00352 2/20 0.33
NFE2L2 Q16236 1/20 0.33
ALOX15 P16050 1/20 0.33
NOTUM Q6P988 1/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
GAA P10253 2/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
TAAR1 Q96RJ0 3/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
NFKB1 P19838 1/20 0.30
NFKB2 Q00653 1/20 0.30
KMT2A Q03164 1/20 0.30
RELA Q04206 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1459198 0.81 TSHR (0.32) ACHEALDH1A1
SCHEMBL3792566 0.79 ACHE (0.38) ACHEALDH1A1NFE2L2ALOX15NOTUM
SCHEMBL8932025 0.79 ACHE (0.43) ACHENFE2L2NOTUMSMN1; SMN2GAA
SCHEMBL15091550 0.77 ACHE (0.42) ACHEALDH1A1NFE2L2NOTUMSMN1; SMN2
SCHEMBL18692020 0.75 ACHE (0.46) ACHEALDH1A1NFE2L2ALOX15NOTUM
SCHEMBL13621359 0.73 ACHE (0.39) ACHEALDH1A1NFE2L2NOTUMSMN1; SMN2
SCHEMBL1302209 0.72 TSHR (0.45) ACHEALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL1798315 0.72 TSHR (0.45) ALDH1A1NOTUMSMN1; SMN2NPC1RAB9A
Hydrochloric Acid SCHEMBL19405531 0.71 ACHE (0.37) ACHENFE2L2NOTUMSMN1; SMN2GAA
Boric Acid SCHEMBL29277889 0.71 ACHE (0.37) ACHEALDH1A1NFE2L2ALOX15GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105820580-A High-strength silicone rubber electromagnetic shielding material and preparing method thereof 东莞市联洲知识产权运营管理有限公司 2016-08-03 CN disclosed