SCHEMBL28071880

SCHEMBL28071880

CCOC(=O)CC(CC(=O)O)C(=O)OCC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.49
MEN1 O00255 1/20 0.49
NPC1 O15118 1/20 0.49
MGAM O43451 1/20 0.44
GAA P10253 1/20 0.44
SI P14410 1/20 0.44
MGAM2 Q2M2H8 1/20 0.44
ALDH1A1 P00352 6/20 0.42
TSHR P16473 2/20 0.42
ALOX15 P16050 3/20 0.42
CYP3A4 P08684 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
TRPA1 O75762 1/20 0.41
HSD17B10 Q99714 2/20 0.41
CHRM1 P11229 1/20 0.41
ADORA1 P30542 1/20 0.41
HCAR2 Q8TDS4 1/20 0.38
CYP2D6 P10635 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8719366 0.91 MGAM (0.52) KMT2AMEN1NPC1MGAMGAA
SCHEMBL7767241 0.88 MGAM (0.44) KMT2AMEN1NPC1MGAMGAA
SCHEMBL2826140 0.83 MEN1 (0.49) KMT2AMEN1NPC1MGAMGAA
SCHEMBL3426953 0.83 KMT2A (0.44) KMT2AMEN1NPC1MGAMGAA
SCHEMBL2709164 0.83 MEN1 (0.47) KMT2AMEN1NPC1MGAMGAA
SCHEMBL9203447 0.83 MGAM (0.48) KMT2AMEN1NPC1MGAMGAA
SCHEMBL6868422 0.83 MGAM (0.48) KMT2AMEN1NPC1MGAMGAA
Water SCHEMBL5017516 0.82 MEN1 (0.47) KMT2AMEN1NPC1MGAMGAA
SCHEMBL733874 0.81 MEN1 (0.46) KMT2AMEN1NPC1MGAMGAA
SCHEMBL9055012 0.81 MGAM (0.46) KMT2AMEN1NPC1MGAMGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104597196-B Treat the discrimination method of ardisia japonica in the Chinese patent drug of hot heavy breathing disease DONG-E DONKEY-HIDE GELATIN CO., LTD., SHANDONG PROV. (CN) 2016-05-25 CN disclosed