SCHEMBL733874

SCHEMBL733874

CCOC(=O)C(CO)CC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.46
NPC1 O15118 1/20 0.46
KMT2A Q03164 1/20 0.46
HCAR2 Q8TDS4 1/20 0.39
ALDH1A1 P00352 4/20 0.39
LMNA P02545 1/20 0.37
HSD17B10 Q99714 1/20 0.37
CPB2 Q96IY4 1/20 0.37
MME P08473 2/20 0.36
ALOX15 P16050 1/20 0.36
MGAM O43451 1/20 0.36
GAA P10253 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
SOAT1 P35610 1/20 0.36
FOLH1 Q04609 1/20 0.35
CYP2D6 P10635 2/20 0.35
EGLN1 Q9GZT9 1/20 0.35
PIN1 Q13526 1/20 0.35
SLC22A6 Q4U2R8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL5878587 0.98 MEN1 (0.44) MEN1NPC1KMT2AHCAR2ALDH1A1
Chloroform SCHEMBL7898866 0.94 MEN1 (0.42) MEN1NPC1KMT2AHCAR2ALDH1A1
Methylene Chloride SCHEMBL4052423 0.94 MEN1 (0.42) MEN1NPC1KMT2AHCAR2ALDH1A1
Hexane SCHEMBL3085310 0.92 GPR84 (0.43) MEN1NPC1KMT2AALDH1A1LMNA
Heptane SCHEMBL7082305 0.91 GPR84 (0.46) MEN1NPC1KMT2AALDH1A1HSD17B10
SCHEMBL2709164 0.84 MEN1 (0.47) MEN1NPC1KMT2AHCAR2ALDH1A1
SCHEMBL3316813 0.84 ALDH1A1 (0.48) MEN1NPC1KMT2AHCAR2ALDH1A1
SCHEMBL1305960 0.83 MEN1 (0.43) MEN1NPC1KMT2AHCAR2ALDH1A1
Ethylene Glycol SCHEMBL27753029 0.83 MEN1 (0.43) MEN1NPC1KMT2AHCAR2ALDH1A1
SCHEMBL9055012 0.83 MGAM (0.46) MEN1NPC1KMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 431 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115369045-B Marine aspergillus fungus and application and analysis method thereof 厦门医学院 2023-06-27 CN claimed
CN-115873009-A Method for extracting and purifying AFB1, AFB2, AFG1 and AFG2 青岛普瑞邦生物工程有限公司 2023-03-31 CN claimed
CN-115369045-A Marine aspergillus fungi and application and analysis method thereof 厦门医学院 2022-11-22 CN claimed
US-10017489-B2 Method for preparing benzopyran compound and application thereof in treating pulmonary fibrosis SHANGHAI JIAO TONG UNIVERSITY (CN) 2018-07-10 US claimed
CN-104593275-B Panus rudis chlorine ketene compound and preparation method and application thereof 厦门大学 2017-04-12 CN claimed
US-20160185742-A1 Method for Preparing Benzopyran Compound and Application thereof in Treating Pulmonary Fibrosis UNIV SHANGHAI JIAOTONG (CN) 2016-06-30 US claimed
CN-104593275-A Panus rudis chlorine ketene compound and preparation method and application thereof UNIV XIAMEN 2015-05-06 CN claimed
CN-118221620-A Benzamide phenylpiperazine radioactive compound and preparation method and application thereof 中国科学院高能物理研究所 2024-06-21 CN disclosed
US-11970731-B2 Enhancement of nucleic acid polymerization by aromatic compounds Roche Sequencing Solutions, Inc. (US) 2024-04-30 US disclosed
US-20230364248-A1 MIC-1 COMPOUNDS AND USES THEREOF NOVO NORDISK AS (DK) 2023-11-16 US disclosed
US-11746111-B2 Siderophore conjugated pyrazolidinones, and analogues thereof YALE UNIVERSITY (US) 2023-09-05 US disclosed
CN-115369045-B Marine aspergillus fungus and application and analysis method thereof 厦门医学院 2023-06-27 CN disclosed
CN-113640450-B Thin-layer chromatography identification method for false yellow Pi Yaocai 海南医学院 2023-06-16 CN disclosed
US-4138589-A CHEMICAL INTERMEDIATES FOR COMPOUNDS USED AS X-RAY CONTRAST AGENTS MALLINCKRODT, INC. (US) 1979-02-06 US disclosed
US-4125709-A X-RAY CONTRAST AGENTS MALLINCKRODT, INC. (US) 1978-11-14 US disclosed
US-4103008-A ANTIBIOTICS TOSHIYASU ISHIMARU 1978-07-25 US disclosed
US-4097586-A Immunochemical assay method BIOLOGICAL DEVELOPMENTS, INC. (US) 1978-06-27 US disclosed
US-4069250-A X-RAY CONTRAST AGENTS MALLINCKRODT, INC. (US) 1978-01-17 US disclosed
US-3953497-A X-RAY CONTRAST AGENTS MALLINCKRODT, INC. (US) 1976-04-27 US disclosed
US-3940475-A Radioimmune method of assaying quantitatively for a hapten BIOLOGICAL DEVELOPMENTS, INC. (US) 1976-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11746111-B2 Siderophore conjugated pyrazolidinones, and analogues thereof SLC40A1, HAMP, SLC39A11 MEN1 1488/4885NPC1 748/4885KMT2A 3711/4885
US-20230364248-A1 MIC-1 COMPOUNDS AND USES THEREOF IMMT, MICA, TAP1 MEN1 142/4885NPC1 610/4885KMT2A 4689/4885
US-10017489-B2 Method for preparing benzopyran compound and application thereof in treating pulmonary fibrosis H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CCNC, FIBP MEN1 1456/4885NPC1 3874/4885KMT2A 4348/4885
US-20160185742-A1 Method for Preparing Benzopyran Compound and Application thereof in Treating Pulmonary Fibrosis H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CCNC, FIBP MEN1 1456/4885NPC1 3874/4885KMT2A 4348/4885
US-11970731-B2 Enhancement of nucleic acid polymerization by aromatic compounds POLN, POLB, POLRMT MEN1 2134/4885NPC1 1613/4885KMT2A 762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.