SCHEMBL28072097

SCHEMBL28072097

[CH2]C(CC(=O)O)c1csc(N)n1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.49
GABRA5 P31644 1/20 0.49
GABRB2 P47870 1/20 0.49
ALDH1A1 P00352 5/20 0.38
KDM4E B2RXH2 2/20 0.38
BACE1 P56817 2/20 0.38
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
MAPT P10636 2/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
KDM6B O15054 1/20 0.35
KDM4A O75164 1/20 0.35
KDM4B O94953 1/20 0.35
KDM5C P41229 1/20 0.35
KDM5B Q9UGL1 1/20 0.35
KDM2A Q9Y2K7 1/20 0.35
KDM3A Q9Y4C1 1/20 0.35
TSHR P16473 1/20 0.34
NOS1 P29475 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10824171 0.76 GABRA5 (0.45) HSD17B10GABRA5GABRB2ALDH1A1KDM4E
SCHEMBL9876692 0.76 GABRA5 (0.45) HSD17B10GABRA5GABRB2ALDH1A1KDM4E
SCHEMBL27383162 0.76
SCHEMBL10506090 0.73 HSD17B10 (0.47) HSD17B10GABRA5GABRB2ALDH1A1KDM4E
SCHEMBL27684641 0.72 HSD17B10 (0.43) HSD17B10GABRA5GABRB2ALDH1A1KDM4E
SCHEMBL4258592 0.72
SCHEMBL7192491 0.72 HSD17B10 (0.46) HSD17B10GABRA5GABRB2ALDH1A1KDM4E
SCHEMBL1565803 0.72 HSD17B10 (0.46) HSD17B10GABRA5GABRB2ALDH1A1KDM4E
SCHEMBL14003554 0.72 GABRA5 (0.46) HSD17B10GABRA5GABRB2ALDH1A1KDM4E
Hydrochloric Acid SCHEMBL1758691 0.70 HSD17B10 (0.44) HSD17B10GABRA5GABRB2ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105820289-A Amino acid grafted glycidyl methacrylate (GMA)-divinyl benzene (DVB) copolymer chelate resin and preparation method and application 哈尔滨工程大学 2016-08-03 CN disclosed