Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM4B | O94953 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28072097 | 0.76 | HSD17B10 (0.49) | GABRA5GABRB2HSD17B10ALDH1A1MAPT | |
| SCHEMBL27383162 | 0.72 | — | — | |
| SCHEMBL10506090 | 0.70 | HSD17B10 (0.47) | GABRA5GABRB2HSD17B10ALDH1A1MAPT | |
| SCHEMBL4258592 | 0.68 | — | — | |
| SCHEMBL1565803 | 0.68 | HSD17B10 (0.46) | GABRA5GABRB2HSD17B10ALDH1A1MAPT | |
| SCHEMBL7192491 | 0.68 | HSD17B10 (0.46) | GABRA5GABRB2HSD17B10ALDH1A1MAPT | |
| SCHEMBL14003554 | 0.68 | GABRA5 (0.46) | GABRA5GABRB2HSD17B10ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL1758691 | 0.67 | HSD17B10 (0.44) | GABRA5GABRB2HSD17B10ALDH1A1MAPT | |
| SCHEMBL999291 | 0.67 | GABRA5 (0.45) | GABRA5GABRB2HSD17B10ALDH1A1MAPT | |
| SCHEMBL8871075 | 0.67 | HSD17B10 (0.41) | GABRA5GABRB2HSD17B10ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011938-A | Antimicrobials | ELI LILLY AND COMPANY (US) | 1991-04-30 | — | — | US | disclosed |