Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 1.00 |
| ▸ | MAPT | P10636 | 10/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 9/20 | 1.00 |
| ▸ | MEN1 | O00255 | 8/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 8/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 7/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 7/20 | 1.00 |
| ▸ | ABCB1 | P08183 | 7/20 | 1.00 |
| ▸ | HPGD | P15428 | 5/20 | 1.00 |
| ▸ | USP2 | O75604 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 5/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 5/20 | 1.00 |
| ▸ | DRD1 | P21728 | 5/20 | 1.00 |
| ▸ | DRD3 | P35462 | 5/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 4/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 1.00 |
| ▸ | DRD2 | P14416 | 4/20 | 1.00 |
| ▸ | ADRA2B | P18089 | 4/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ergocryptine SCHEMBL30498875 | 1.00 | KDM4E (1.00) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| Ergocryptine SCHEMBL29372991 | 1.00 | KDM4E (1.00) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| Ergocryptine SCHEMBL29376491 | 1.00 | KDM4E (1.00) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| Ergocryptine SCHEMBL78951 | 1.00 | KDM4E (1.00) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| Ergocryptine SCHEMBL11034170 | 1.00 | KDM4E (1.00) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| Ergocryptine SCHEMBL12481541 | 0.98 | KDM4E (0.95) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| SCHEMBL30449023 | 0.94 | MAPT (0.88) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| Ergocristine SCHEMBL29386896 | 0.93 | MAPT (0.89) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| Ergocristine SCHEMBL30957132 | 0.92 | CYP2C9 (1.00) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| Ergocristine SCHEMBL14029486 | 0.92 | CYP2C9 (1.00) | KDM4EMAPTCYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118209655-A | Method for detecting ergot alkaloid in food | 安徽省疾病预防控制中心(省健康教育所、省公共卫生研究院) | 2024-06-18 | — | — | CN | disclosed |
| CN-112521407-B | Preparation of bromocriptine mesylate | 天津康哲医药科技发展有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-112521407-A | Preparation of bromocriptine mesylate | 天津康哲医药科技发展有限公司 | 2021-03-19 | — | — | CN | disclosed |
| CN-105560244-B | A kind of inhibitors of gamma-secretase and its application | 上海交通大学 | 2019-01-11 | — | — | CN | disclosed |
| CN-105560244-A | Gamma-secretase inhibitor and use thereof | UNIV SHANGHAI JIAOTONG | 2016-05-11 | — | — | CN | disclosed |