Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 11/20 | 1.00 |
| ▸ | MAPT | P10636 | 10/20 | 1.00 |
| ▸ | MEN1 | O00255 | 9/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 9/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 9/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | ABCB1 | P08183 | 6/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 5/20 | 1.00 |
| ▸ | HPGD | P15428 | 5/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | THRB | P10828 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.86 |
| ▸ | USP2 | O75604 | 5/20 | 0.86 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.86 |
| ▸ | DRD2 | P14416 | 5/20 | 0.86 |
| ▸ | ADRA2B | P18089 | 5/20 | 0.86 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.86 |
| ▸ | DRD1 | P21728 | 5/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ergocristine SCHEMBL4947691 | 1.00 | CYP2C9 (1.00) | CYP2C9MAPTMEN1KMT2ACYP2C19 | |
| Ergocristine SCHEMBL30957132 | 1.00 | CYP2C9 (1.00) | CYP2C9MAPTMEN1KMT2ACYP2C19 | |
| Ergocristine SCHEMBL455906 | 1.00 | CYP2C9 (1.00) | CYP2C9MAPTMEN1KMT2ACYP2C19 | |
| Ergocristine SCHEMBL177877 | 1.00 | CYP2C9 (1.00) | CYP2C9MAPTMEN1KMT2ACYP2C19 | |
| Ergocristine SCHEMBL20136277 | 0.98 | CYP2C9 (0.96) | CYP2C9MAPTMEN1KMT2ACYP2C19 | |
| Ergocristine SCHEMBL11081603 | 0.98 | CYP2C9 (0.96) | CYP2C9MAPTMEN1KMT2ACYP2C19 | |
| Ergocristine SCHEMBL18208064 | 0.98 | CYP2C9 (0.96) | CYP2C9MAPTMEN1KMT2ACYP2C19 | |
| Ergocristine SCHEMBL29386896 | 0.94 | MAPT (0.89) | CYP2C9MAPTMEN1KMT2ACYP2C19 | |
| Ergocryptine SCHEMBL78951 | 0.92 | KDM4E (1.00) | CYP2C9MAPTMEN1KMT2ACYP2C19 | |
| Ergocryptine SCHEMBL11034170 | 0.92 | KDM4E (1.00) | CYP2C9MAPTMEN1KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080267948-A1 | Croos-B Structure Binding Compounds | CROSSBETA BIOSCIENCES B.V. (NL) | 2008-10-30 | — | — | US | disclosed |
| US-20080267948-A1 | Croos-B Structure Binding Compounds | CROSSBETA BIOSCIENCES B.V. (NL) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080267948-A1 | Croos-B Structure Binding Compounds | CACYBP, TBCB, MYCBP | CYP2C9 4497/4885MAPT 2206/4885MEN1 4546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.