Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 1.00 |
| ▸ | MAPT | P10636 | 10/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 9/20 | 1.00 |
| ▸ | MEN1 | O00255 | 8/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 8/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 7/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 7/20 | 1.00 |
| ▸ | ABCB1 | P08183 | 7/20 | 1.00 |
| ▸ | HPGD | P15428 | 5/20 | 1.00 |
| ▸ | USP2 | O75604 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 5/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 5/20 | 1.00 |
| ▸ | DRD1 | P21728 | 5/20 | 1.00 |
| ▸ | DRD3 | P35462 | 5/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 4/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 1.00 |
| ▸ | DRD2 | P14416 | 4/20 | 1.00 |
| ▸ | ADRA2B | P18089 | 4/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ergocryptine SCHEMBL30498875 | 1.00 | KDM4E (1.00) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| Ergocryptine SCHEMBL29372991 | 1.00 | KDM4E (1.00) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| Ergocryptine SCHEMBL28072302 | 1.00 | KDM4E (1.00) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| Ergocryptine SCHEMBL29376491 | 1.00 | KDM4E (1.00) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| Ergocryptine SCHEMBL11034170 | 1.00 | KDM4E (1.00) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| Ergocryptine SCHEMBL12481541 | 0.98 | KDM4E (0.95) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| SCHEMBL30449023 | 0.94 | MAPT (0.88) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| Ergocristine SCHEMBL29386896 | 0.93 | MAPT (0.89) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| Ergocristine SCHEMBL30957132 | 0.92 | CYP2C9 (1.00) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| Ergocristine SCHEMBL14029486 | 0.92 | CYP2C9 (1.00) | KDM4EMAPTCYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1651 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026043908-A1 | COMPOSITIONS AND METHODS TO IMPROVE SEQUESTRATION OF MYCOTOXINS AND THEIR USE IN DETOXIFICATION OF ANIMAL FEED AND ANIMAL PRODUCTION SYSTEMS | ALLTECH, INC. (US) | 2026-02-26 | — | — | WO | claimed |
| EP-4220161-A1 | A BUFFER SYSTEM FOR PARTICLE-BASED MULTIPLEXED IMMUNOASSAYS | Bundesrepublik Deutschland, vertreten durch den Bundesminister für Wirtschaft und Energie (DE) | 2023-08-02 | — | — | EP | claimed |
| CN-115578347-A | Quantitative analysis method, system and equipment for LHI cerebral edema based on deep learning | 河北医科大学第二医院 | 2023-01-06 | — | — | CN | claimed |
| US-20200222386-A1 | AGENT FOR PREVENTING AND/OR TREATING ALZHEIMER'S DISEASE | KYOTO UNIVERSITY (JP) | 2020-07-16 | — | — | US | claimed |
| EP-3646872-A1 | AGENT FOR PREVENTING AND/OR TREATING ALZHEIMER'S DISEASE | Kyoto University (JP) | 2020-05-06 | — | — | EP | claimed |
| CN-102026618-B | parenteral formulations of dopamine agonists | 维罗科学有限责任公司 | 2017-07-14 | — | — | CN | claimed |
| EP-1881853-B1 | ALL-OVER COATING OF VESSEL STENTS | HEMOTEQ AG (DE) | 2016-09-28 | — | — | EP | claimed |
| CN-105879035-A | METHODS AND SYSTEMS FOR TREATMENT OF MIGRAINES AND OTHER INDICATIONS | 战略科学与技术有限责任公司 | 2016-08-24 | — | — | CN | claimed |
| CN-103517708-B | Pharmaceutical composition | Kozateko Briksk (HR) | 2016-02-17 | — | — | CN | claimed |
| US-20150031719-A1 | Topical Therapy for the Treatment of Migraines, Muscle Sprains, Muscle Spasms, Spasticity and Related Conditions | AFGIN PHARMA LLC | 2015-01-29 | — | — | US | claimed |
| WO-2000012075-A1 | NITROSATED AND NITROSYLATED ALPHA-ADRENERGIC RECEPTOR ANTAGONISTS, COMPOSITIONS AND METHODS OF USE | NITROMED, INC. (US) | 2000-03-09 | — | — | WO | claimed |
| WO-1997027749-A1 | NITROSATED AND NITROSYLATED α-ADRENERGIC RECEPTOR ANTAGONIST COMPOUNDS, COMPOSITIONS AND THEIR USES | NITROMED, INC. (US) | 1997-08-07 | — | — | WO | claimed |
| US-5573776-A | Oral osmotic device with hydrogel driving member | ALZA CORPORATION (US) | 1996-11-12 | — | — | US | claimed |
| US-5468486-A | Vaccine containing a protein alkaloid conjugate for the treatment of fescue toxicosis | THE UNIVERSITY OF TENNESSEE RESEARCH CORPORATION (US) | 1995-11-21 | — | — | US | claimed |
| EP-0251732-B1 | PROCESS FOR THE PREPARATION OF 2-HALOGENATED ERGOLINE DERIVATIVES | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1993-04-28 | — | — | EP | claimed |
| US-4816587-A | Process for the preparation of 2-halogenated ergoline derivatives | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1989-03-28 | — | — | US | claimed |
| US-4697017-A | Process for the preparation of 2-bromo-α-ergocryptine | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1987-09-29 | — | — | US | claimed |
| US-4609731-A | Process for brominating ergot alkaloids | SANDOZ LTD. (CH) | 1986-09-02 | — | — | US | claimed |
| US-4390625-A | ERGOCORNINE AND ERGOCRYPTINE | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1983-06-28 | — | — | US | claimed |
| US-4202897-A | IMIDAZON2,1-AE ISOINDOLES AND ISOQUINOLINES | SANDOZ, INC. (US) | 1980-05-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200222386-A1 | AGENT FOR PREVENTING AND/OR TREATING ALZHEIMER'S DISEASE | PSEN1, APP, PSEN2 | KDM4E 4134/4885MAPT 6/4885CYP3A4 4667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.