Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 4/20 | 0.37 |
| ▸ | APEX1 | P27695 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ubiquinone Qo SCHEMBL49420 | 0.84 | HKDC1 (0.61) | HKDC1MAPTHPGDKDM4ETP53 | |
| Ubiquinone Qo SCHEMBL742862 | 0.77 | HKDC1 (0.53) | HKDC1MAPTHPGDKDM4ETP53 | |
| Ubiquinone Qo SCHEMBL2211118 | 0.77 | HKDC1 (0.53) | HKDC1MAPTHPGDKDM4ETP53 | |
| Menadione SCHEMBL29172353 | 0.73 | ALDH1A1 (0.70) | HKDC1MAPTHPGDKDM4ETP53 | |
| Ubiquinone Qo SCHEMBL6760403 | 0.72 | HKDC1 (0.63) | HKDC1MAPTKDM4ETP53LMNA | |
| SCHEMBL10787959 | 0.72 | HKDC1 (0.50) | HKDC1MAPTHPGDKDM4ETP53 | |
| SCHEMBL11572784 | 0.71 | ALDH1A1 (0.47) | HKDC1MAPTHPGDKDM4ETP53 | |
| SCHEMBL1915628 | 0.71 | HKDC1 (0.45) | HKDC1MAPTHPGDKDM4ETP53 | |
| SCHEMBL14894669 | 0.70 | ALDH1A1 (0.50) | HKDC1MAPTHPGDKDM4ETP53 | |
| Ubiquinone Qo SCHEMBL28257488 | 0.69 | MAPT (0.57) | HKDC1MAPTHPGDKDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105705162-A | Method for treating cancer by continuous infusion of coenzyme Q10 | 博格有限责任公司 | 2016-06-22 | — | — | CN | disclosed |