Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.42 |
| ▸ | AR | P10275 | 3/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28347876 | 0.82 | CYP11B1 (0.50) | MAOAARCYP11B1CYP11B2KDM4E | |
| SCHEMBL30021816 | 0.82 | CYP11B1 (0.50) | MAOAARCYP11B1CYP11B2KDM4E | |
| SCHEMBL981232 | 0.79 | CYP11B2 (0.65) | MAOACYP11B1CYP11B2 | |
| SCHEMBL980699 | 0.76 | CYP11B1 (0.49) | MAOAMAP4K4CYP11B1CYP11B2CA12 | |
| SCHEMBL1143483 | 0.74 | MAOA (0.59) | MAOAMAP4K4CYP11B1CYP11B2CA12 | |
| Water SCHEMBL3862803 | 0.74 | MAOA (0.79) | MAOAMAP4K4CYP11B1CYP11B2CA12 | |
| Water SCHEMBL2444002 | 0.74 | MAOA (0.79) | MAOAMAP4K4CYP11B1CYP11B2CA12 | |
| SCHEMBL29561461 | 0.72 | MAOA (0.84) | MAOAMAP4K4CYP11B1CYP11B2CA12 | |
| SCHEMBL29394565 | 0.72 | MAOA (0.84) | MAOAMAP4K4CYP11B1CYP11B2CA12 | |
| SCHEMBL311194 | 0.72 | MAOA (0.84) | MAOAMAP4K4CYP11B1CYP11B2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105829285-A | Quinazolinone and isoquinolinone derivatives | 中外制药株式会社 | 2016-08-03 | — | — | CN | disclosed |