SCHEMBL28073079

SCHEMBL28073079

CC=CC(=O)OCc1ccc(C(=O)O)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.51
LMNA P02545 1/20 0.49
RXRA P19793 7/20 0.47
RXRB P28702 6/20 0.47
NPC1 O15118 1/20 0.47
POLB P06746 1/20 0.47
RAB9A P51151 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
ALDH1A1 P00352 2/20 0.47
EGFR P00533 1/20 0.46
BTK Q06187 1/20 0.46
RXRG P48443 1/20 0.45
CA12 O43570 1/20 0.45
AKR1B10 O60218 1/20 0.45
AKR1B1 P15121 1/20 0.45
CA4 P22748 1/20 0.45
CA6 P23280 1/20 0.45
CA5A P35218 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8075727 0.89 HCAR2 (0.47) HCAR2LMNARXRARXRBNPC1
SCHEMBL1070426 0.84 HCAR2 (0.71) HCAR2LMNAPOLBALDH1A1EGFR
SCHEMBL29063508 0.84 HCAR2 (0.51) HCAR2LMNAPOLBALDH1A1EGFR
SCHEMBL1070423 0.84 HCAR2 (0.71) HCAR2LMNAPOLBALDH1A1EGFR
SCHEMBL20211557 0.84 HCAR2 (0.51) HCAR2LMNANPC1POLBRAB9A
SCHEMBL14936847 0.83 HCAR2 (0.50) HCAR2LMNANPC1RAB9AALDH1A1
SCHEMBL14936845 0.83 HCAR2 (0.50) HCAR2LMNANPC1RAB9AALDH1A1
SCHEMBL28186376 0.82 HCAR2 (0.58) HCAR2LMNANPC1POLBRAB9A
SCHEMBL28073168 0.81 MRGPRX4 (0.52) HCAR2RAB9ASMN1; SMN2EGFRBTK
SCHEMBL14936903 0.81 HCAR2 (0.49) HCAR2LMNAALDH1A1EGFRBTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105705580-A (meth) acrylic copolymer, resin composition, and molded article thereof 三菱瓦斯化学株式会社 2016-06-22 CN disclosed