SCHEMBL28186376

SCHEMBL28186376

CC=CC(=O)OCc1ccc(-c2ccccc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.58
LMNA P02545 2/20 0.55
AKR1B10 O60218 2/20 0.51
AKR1B1 P15121 2/20 0.51
CA12 O43570 2/20 0.51
CA4 P22748 2/20 0.51
CA6 P23280 2/20 0.51
CA5A P35218 2/20 0.51
CA7 P43166 2/20 0.51
CA9 Q16790 2/20 0.51
CA14 Q9ULX7 2/20 0.51
CA5B Q9Y2D0 2/20 0.51
EGFR P00533 1/20 0.51
BTK Q06187 1/20 0.51
RAB9A P51151 2/20 0.49
NPC1 O15118 1/20 0.49
ALDH1A1 P00352 3/20 0.47
TTR P02766 1/20 0.47
EPHX1 P07099 1/20 0.46
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20211557 0.93 HCAR2 (0.51) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL1070426 0.90 HCAR2 (0.71) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL1070423 0.90 HCAR2 (0.71) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL28081360 0.84 HCAR2 (0.63) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL29063518 0.83 HCAR2 (0.54) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL29063508 0.83 HCAR2 (0.51) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL28073079 0.82 HCAR2 (0.51) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL14936845 0.81 HCAR2 (0.50) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL14936847 0.81 HCAR2 (0.50) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL2435314 0.80 HCAR2 (0.53) HCAR2LMNAAKR1B10AKR1B1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116693384-A Preparation method of beta, gamma-unsaturated carboxylic acid benzyl ester compound 大连理工大学 2023-09-05 CN disclosed
CN-107406654-B Resin composition and molded article using same 三菱瓦斯化学株式会社 2019-03-08 CN disclosed
CN-107406654-A Resin composition and molded article using same 三菱瓦斯化学株式会社 2017-11-28 CN disclosed