SCHEMBL28073103

SCHEMBL28073103

COC(=O)C(C)(C)COC(C)OC

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8295843 0.83 DGAT1 (0.35) DGAT1
SCHEMBL16862190 0.82 CYP4F2 (0.31)
SCHEMBL16862047 0.82 ACACB (0.37)
SCHEMBL28173674 0.77
SCHEMBL16862075 0.76 CYP2C9 (0.33)
SCHEMBL17574066 0.75 DGAT1 (0.42) DGAT1
SCHEMBL18552877 0.74
SCHEMBL12413765 0.73 ALDH1A1 (0.35) DGAT1
SCHEMBL1012154 0.73 DGAT1 (0.41) DGAT1
SCHEMBL20428848 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105705508-B Acyclonucleosides phosphoric acid ester derivant and preparation method thereof and application medically 四川海思科制药有限公司 2017-09-01 CN disclosed
CN-105705508-A Acyclic nucleoside phosphonate derivative and preparation method and use thereof in medical science 四川海思科制药有限公司 2016-06-22 CN disclosed