SCHEMBL28073151

SCHEMBL28073151

Cc1ccc(-c2ccc(O)cc2)c(C2(C)CCCCC2)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.43
TSHR P16473 1/20 0.43
ALOX12 P18054 1/20 0.43
ESR1 P03372 4/20 0.41
ESR2 Q92731 4/20 0.41
RARB P10826 2/20 0.39
RARG P13631 2/20 0.39
PTPN11 Q06124 1/20 0.39
NPSR1 Q6W5P4 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
ATM Q13315 1/20 0.38
HSD17B10 Q99714 1/20 0.38
MAOB P27338 1/20 0.38
ESRRA P11474 1/20 0.36
GAA P10253 2/20 0.36
MGAM O43451 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
ACHE P22303 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL224914 0.79 ALOX12 (0.50) GLATSHRALOX12ESR1ESR2
SCHEMBL28067744 0.78 GLA (0.45) GLATSHRALOX12ESR1ESR2
SCHEMBL224293 0.71 GLA (0.66) GLATSHRALOX12ESR1ESR2
SCHEMBL28101898 0.71 PTGDR2 (0.45) ESR1ESR2KMT2AMAOBGAA
SCHEMBL10899122 0.70 RARB (0.50) GLATSHRALOX12ESR1ESR2
SCHEMBL2498796 0.69 GLA (0.48) GLATSHRALOX12RARBRARG
SCHEMBL1513689 0.69 ESR2 (0.60) ESR1ESR2HSD17B10MAOBESRRA
SCHEMBL6897471 0.69 ESRRA (0.61) TSHRESR1ESR2MAOBESRRA
SCHEMBL29637921 0.69 ESRRA (0.61) TSHRESR1ESR2MAOBESRRA
SCHEMBL28193429 0.68 ESRRA (0.53) TSHRESR1ESR2HSD17B10MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110446732-A The polyurethane discharged with reduced aldehyde DOW GLOBAL TECHNOLOGIES LLC 2019-11-12 CN disclosed
CN-110446733-A The polyurethane foam discharged with reduced aldehyde DOW GLOBAL TECHNOLOGIES LLC 2019-11-12 CN disclosed
CN-110446731-A Polyurethane foam with low aldehyde emission level DOW GLOBAL TECHNOLOGIES LLC 2019-11-12 CN disclosed
CN-109599371-A Semiconductor devices, its production method and laminated body 信越化学工业株式会社 2019-04-09 CN disclosed
CN-207898025-U Combination vamp and outsole for footwear product 耐克创新有限合伙公司 2018-09-25 CN disclosed
CN-108441163-A A kind of optical cement and preparation method thereof applied to nano silver wire conductive film 合肥微晶材料科技有限公司 2018-08-24 CN disclosed
CN-107919315-A Chip lamilate and preparation method thereof 信越化学工业株式会社 2018-04-17 CN disclosed
CN-107353854-A A kind of OCA optical cements and OCA optical adhesive films 东莞市纳利光学材料有限公司 2017-11-17 CN disclosed
CN-102482261-B Sterically hindered amine stabilizers BASF SE (DE) 2016-05-25 CN disclosed