Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27659022 | 0.79 | GAA (0.31) | GAA | |
| SCHEMBL10772762 | 0.79 | DGAT1 (0.41) | DGAT1ALDH1A1KCNN4TP53RAB9A | |
| SCHEMBL4664424 | 0.79 | DGAT1 (0.41) | DGAT1ALDH1A1KCNN4TP53RAB9A | |
| SCHEMBL29115444 | 0.79 | DGAT1 (0.41) | DGAT1ALDH1A1KCNN4TP53RAB9A | |
| Hydrochloric Acid SCHEMBL4664452 | 0.77 | DGAT1 (0.39) | DGAT1ALDH1A1KCNN4TP53RAB9A | |
| SCHEMBL1866882 | 0.76 | — | — | |
| SCHEMBL27635112 | 0.75 | DGAT1 (0.60) | DGAT1KCNN4 | |
| SCHEMBL27635111 | 0.75 | DGAT1 (0.60) | DGAT1KCNN4 | |
| SCHEMBL5491194 | 0.75 | — | — | |
| SCHEMBL240584 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115297861-B | Compounds and uses thereof | 福宏治疗公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-115297861-A | Compound and use thereof | 福宏治疗公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-105693541-A | Synthetic method of methyldopa | 湖南湘易康制药有限公司 | 2016-06-22 | — | — | CN | disclosed |