Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19178065 | 0.78 | TSHR (0.39) | KDM4EALDH1A1SMN1; SMN2TDP1HTT | |
| SCHEMBL28830043 | 0.78 | KDM4E (0.40) | KDM4EHSD17B10ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL17431289 | 0.69 | PTGS1 (0.35) | HTT | |
| SCHEMBL2114303 | 0.67 | ALDH1A1 (0.45) | KDM4EHSD17B10ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL18719618 | 0.67 | ALDH1A1 (0.52) | KDM4EHSD17B10ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL9731794 | 0.66 | HSD17B10 (0.46) | KDM4EHSD17B10ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL3293016 | 0.65 | ALDH1A1 (0.52) | KDM4EHSD17B10ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL13140675 | 0.65 | HSD17B10 (0.41) | KDM4EHSD17B10ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL1784441 | 0.65 | ALDH1A1 (0.44) | KDM4EHSD17B10ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL15211185 | 0.65 | TSHR (0.38) | KDM4EALDH1A1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104254525-B | aromatic ring compound | TAKEDA PHARMACEUTICAL CO.,LTD. (JP) | 2016-05-25 | — | — | CN | disclosed |