Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Farnesol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.65 |
| ▸ | FNTA | P49354 | 2/20 | 0.50 |
| ▸ | FNTB | P49356 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.50 |
| ▸ | ICMT | O60725 | 1/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Farnesol SCHEMBL3040180 | 0.94 | MAPT (0.61) | MAPTKMT2ACYP3A4MEN1ALOX15 | |
| Geraniol SCHEMBL28645505 | 0.92 | CYP3A4 (0.59) | MAPTKMT2ACYP3A4MEN1ALOX15 | |
| Geraniol SCHEMBL28124083 | 0.89 | TRPV1 (0.55) | MAPTKMT2ACYP3A4MEN1ALOX15 | |
| Benzoic Acid SCHEMBL11308732 | 0.86 | SQLE (0.57) | MAPTKMT2ACYP3A4MEN1ALOX15 | |
| Benzoic Acid SCHEMBL11301240 | 0.86 | SQLE (0.57) | MAPTKMT2ACYP3A4MEN1ALOX15 | |
| Plaunotol SCHEMBL11303873 | 0.86 | SQLE (0.57) | MAPTKMT2ACYP3A4MEN1ALOX15 | |
| Benzoic Acid SCHEMBL11303886 | 0.84 | SQLE (0.55) | MAPTKMT2ACYP3A4MEN1ALOX15 | |
| SCHEMBL11052318 | 0.84 | POLB (0.50) | MAPTKMT2ACYP3A4MEN1ALDH1A1 | |
| SCHEMBL9288443 | 0.84 | POLB (0.50) | MAPTKMT2ACYP3A4MEN1ALDH1A1 | |
| Geranylgeraniol SCHEMBL1573864 | 0.84 | KMT2A (0.83) | MAPTKMT2ACYP3A4MEN1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105722960-B | Lubricating composition containing the component based on isoprene | 卡斯特罗尔有限公司 | 2019-04-30 | — | — | CN | disclosed |
| CN-105722960-A | Lubricating compositions containing isoprene based components | 卡斯特罗尔有限公司 | 2016-06-29 | — | — | CN | disclosed |