Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Farnesol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.61 |
| ▸ | ICMT | O60725 | 1/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Geraniol SCHEMBL28645505 | 0.98 | CYP3A4 (0.59) | MAPTCYP3A4KMT2AMEN1ALOX15 | |
| Farnesol SCHEMBL28074103 | 0.94 | MAPT (0.65) | MAPTCYP3A4KMT2AMEN1ALOX15 | |
| Benzoic Acid SCHEMBL11301240 | 0.92 | SQLE (0.57) | MAPTCYP3A4KMT2AMEN1ALOX15 | |
| Benzoic Acid SCHEMBL11308732 | 0.92 | SQLE (0.57) | MAPTCYP3A4KMT2AMEN1ALOX15 | |
| Plaunotol SCHEMBL11303873 | 0.92 | SQLE (0.57) | MAPTCYP3A4KMT2AMEN1ALOX15 | |
| Benzoic Acid SCHEMBL11303886 | 0.90 | SQLE (0.55) | MAPTCYP3A4KMT2AMEN1ALOX15 | |
| Farnesol SCHEMBL9270279 | 0.87 | MAPT (0.56) | MAPTCYP3A4KMT2AMEN1ALOX15 | |
| SCHEMBL19665178 | 0.83 | MAPT (0.49) | MAPTCYP3A4KMT2AMEN1ALOX15 | |
| Geraniol SCHEMBL28124083 | 0.83 | TRPV1 (0.55) | MAPTCYP3A4KMT2AMEN1ALOX15 | |
| Farnesol SCHEMBL6072528 | 0.83 | MAPT (0.60) | MAPTCYP3A4KMT2AMEN1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100222606-A1 | METHOD FOR PRODUCING BISABOLOL WHICH IS FARNESOL FREE OR IS LOW IN FARNESOL | BASF SE (DE) | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222606-A1 | METHOD FOR PRODUCING BISABOLOL WHICH IS FARNESOL FREE OR IS LOW IN FARNESOL | FHIT, FDPS, FNTA | MAPT 1980/4885CYP3A4 156/4885KMT2A 4087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.