SCHEMBL28074288

SCHEMBL28074288

C#Cc1ccc(-c2ccccc2)cc1.[Pt]

nearest known ligand 0.95

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.50
CYP1A1 P04798 1/20 0.50
CYP1B1 Q16678 1/20 0.50
ALDH1A1 P00352 2/20 0.47
TAAR1 Q96RJ0 2/20 0.42
MAPK1 P28482 1/20 0.42
CYP3A4 P08684 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
MMP3 P08254 1/20 0.42
BCL2L1 Q07817 1/20 0.42
KCNH2 Q12809 1/20 0.41
KEAP1 Q14145 1/20 0.41
HDAC8 Q9BY41 1/20 0.40
CYP2C9 P11712 1/20 0.39
PYCR1 P32322 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA4 P22748 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL77549 0.97 CYP1A2 (0.52) CYP1A2CYP1A1CYP1B1ALDH1A1TAAR1
Fluoride SCHEMBL27604190 0.95 CYP1A2 (0.50) CYP1A2CYP1A1CYP1B1ALDH1A1TAAR1
Biphenyl SCHEMBL28621540 0.89 ALDH1A1 (0.53) CYP1A2CYP1A1CYP1B1ALDH1A1TAAR1
Phenylacetylene SCHEMBL29010743 0.89 APP (0.45) CYP1A2CYP1A1CYP1B1ALDH1A1TAAR1
SCHEMBL6347456 0.89 EGLN2 (0.44) CYP1A2CYP1A1CYP1B1ALDH1A1CYP3A4
Biphenyl SCHEMBL27577179 0.86 ALDH1A1 (0.50) CYP1A2CYP1A1CYP1B1ALDH1A1TAAR1
SCHEMBL6752540 0.86 CYP1A1 (0.48) CYP1A2CYP1A1CYP1B1ALDH1A1TDP1
SCHEMBL139848 0.86 HDAC8 (0.50) CYP1A2CYP1A1CYP1B1MMP3KEAP1
SCHEMBL139611 0.86 HDAC8 (0.50) CYP1A2CYP1A1CYP1B1MMP3KEAP1
SCHEMBL10160387 0.84 CYP1A2 (0.42) CYP1A2CYP1A1CYP1B1ALDH1A1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102881296-B Optical data carrier records method and the optical data carrier of data 通用电气公司 2016-07-06 CN claimed
CN-102881296-B Optical data carrier records method and the optical data carrier of data 通用电气公司 2016-07-06 CN disclosed
CN-104903960-A Stacked film reflective layers for multi-layer optical data storage GEN ELECTRIC 2015-09-09 CN disclosed